Clerici Joanna, MacLaran Sarah
ST5 Palliative Medicine, Community Palliative Care Team, Coventry, UK.
BMJ Support Palliat Care. 2014 Mar;4(1):81-3. doi: 10.1136/bmjspcare-2012-000394. Epub 2013 Aug 6.
In the context of palliative medicine, spinal cord compression occurs in around 5% of patients with cancer. Ten per cent of patients with spinal metastases are affected; the commonest causes are breast, prostate, lung cancer and multiple myeloma. We describe a rare cause of spinal cord compression in a 29-year-old man resulting from a complication of long-term corticosteroid use. Spinal epidural lipomatosis is a complex disorder caused by hypertrophy of adipose tissue located in the spinal epidural space. Symptoms occur when the adipose tissue enlarges, encroaching on the spinal canal. In this case, the aetiology was long-term exogenous dexamethasone use.
在姑息医学领域，约5%的癌症患者会发生脊髓压迫。脊髓转移瘤患者中有10%会受到影响；最常见的病因是乳腺癌、前列腺癌、肺癌和多发性骨髓瘤。我们描述了一名29岁男性因长期使用皮质类固醇激素的并发症导致脊髓压迫的罕见病因。脊髓硬膜外脂肪增多症是一种由位于脊髓硬膜外间隙的脂肪组织肥大引起的复杂病症。当脂肪组织增大并侵入椎管时就会出现症状。在本例中，病因是长期外用了地塞米松。
