Partyka Małgorzata, Dunin-Wilczyńska Izabella, Chałas Renata
Pol Merkur Lekarski. 2014 Jan;36(211):63-7.
Growth hormone (GH) is a polypeptide hormone produced by the cells of pituitary. Production of growth hormone is carried out in a pulsating manner, and the frequency and intensity of the pulses is dependent on age and gender. Growth hormone deficiency (GHD) is characterized by, among others, slow growth process often from early childhood, delayed bone age. The aim of the study was to describe dental problems of children with short stature with a special attention on disorders at the craniofacial region such as decreased growth of maxilla and mandible, gnathic and bite dysfunctions, delayed teeth eruption, tooth caries susceptibility. Growth hormone treatment undertaken at the right time significantly influences on correct development of cranial bones and dentition, and supports orthodontic treatment.
生长激素（GH）是一种由垂体细胞产生的多肽激素。生长激素的分泌呈脉冲式，其脉冲频率和强度取决于年龄和性别。生长激素缺乏症（GHD）的特征包括，尤其是从幼儿期开始的生长过程缓慢、骨龄延迟。本研究的目的是描述身材矮小儿童的牙齿问题，特别关注颅面部区域的紊乱情况，如下颌骨和上颌骨生长减缓、颌骨和咬合功能障碍、牙齿萌出延迟、龋齿易感性。适时进行生长激素治疗对颅骨和牙列的正常发育有显著影响，并有助于正畸治疗。
