Varner Paul
John J Pershing Veterans Affairs Medical Center, Poplar Bluff, Missouri, USA.
J Optom. 2014 Jan-Mar;7(1):57-61. doi: 10.1016/j.optom.2013.03.001. Epub 2013 May 7.
To determine if routine dilated fundus examination (DFE) should be performed sooner than at 10-year intervals in asymptomatic patients.
Records for all patients consecutively evaluated in a one-year time frame were systematically reviewed. Of those patients who received initial DFE and were living 10 years later, records for sequential DFE were again evaluated to determine presence of clinically-significant, peripheral retinal findings. Databases were also searched in order to determine the number of patients during the same 10-year time period who developed vision or life-threatening peripheral retinal findings. The two groups were cross-matched to determine effectiveness of routine DFE.
Only 10 of 592 patients were deemed to have "clinically-significant" peripheral retinal findings--none of whom developed untoward outcomes. Of the 29 new retinal detachments and four intraocular tumors discovered during ten years of clinical follow-up, nearly 90% were symptomatic at the time of discovery. Three detachments and one tumor were detected as incidental findings in asymptomatic patients. No further treatment was recommended for the three detachments and the patient with the tumor survives, although with profound loss of vision in the involved eye.
In the absence of symptoms, routine DFE seems to have a very low yield for discovery of serious ocular events and appears to be ineffective in altering the course of incidental findings. Routine DFE is not indicated for older, asymptomatic patients--even at decade intervals. The findings of this study should be prospectively confirmed in population-based studies.
确定无症状患者的常规散瞳眼底检查(DFE)是否应比每10年进行一次的间隔时间更早进行。
系统回顾了在一年时间内连续评估的所有患者的记录。对于那些接受了初次DFE且10年后仍在世的患者,再次评估连续DFE的记录,以确定是否存在具有临床意义的周边视网膜病变。还检索了数据库,以确定在同一10年期间出现视力或危及生命的周边视网膜病变的患者数量。将这两组进行交叉匹配,以确定常规DFE的有效性。
592例患者中只有10例被认为有“具有临床意义的”周边视网膜病变,且无一例出现不良后果。在十年的临床随访中发现的29例新的视网膜脱离和4例眼内肿瘤中,近90%在发现时伴有症状。3例视网膜脱离和1例肿瘤是在无症状患者中作为偶然发现被检测到的。对于这3例视网膜脱离未建议进一步治疗,患有肿瘤的患者存活下来,尽管患眼视力严重丧失。
在无症状的情况下,常规DFE对于发现严重眼部事件的检出率似乎非常低,而且在改变偶然发现的病程方面似乎无效。对于年龄较大的无症状患者,即使间隔十年,也不建议进行常规DFE。本研究的结果应在基于人群的研究中进行前瞻性验证。