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A/B型酒精依赖在普通人群中的适用性。

Applicability of Type A/B alcohol dependence in the general population.

作者信息

Tam Tammy W, Mulia Nina, Schmidt Laura A

机构信息

Alcohol Research Group, Public Health Institute, 6475 Christie Avenue, Suite 400, Emeryville, CA 94608, United States.

Alcohol Research Group, Public Health Institute, 6475 Christie Avenue, Suite 400, Emeryville, CA 94608, United States.

出版信息

Drug Alcohol Depend. 2014 May 1;138:169-76. doi: 10.1016/j.drugalcdep.2014.02.698. Epub 2014 Mar 5.

Abstract

BACKGROUND

This study examined the concurrent and predictive validity of Type A/B alcohol dependence in the general population-a typology developed in clinical populations to gauge severity of dependence.

METHODS

Data were drawn from Waves 1 and 2 of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). The sample included 1,172 alcohol-dependent drinkers at baseline who were reinterviewed three years later. Latent class analysis was used to derive Type A/B classification using variables replicating the original Type A/B typology. Predictive validity of the Type A/B classification was assessed by multivariable linear and logistic regressions.

RESULTS

A two-class solution consistent with Babor's original Type A/B typology adequately fit the data. Type B alcoholics in the general population, compared to Type As, had higher alcohol severity and more co-occurring drug, mental, and physical health problems. In the absence of treatment services utilization, Type B drinkers had two times the odds of being alcohol dependent three years later. Among those who utilized alcohol treatment services, Type B membership was predictive of heavy drinking and drug dependence, but not alcohol dependence, three years later.

CONCLUSIONS

Findings suggest that Type A/B classification is both generalizable to, and valid within, the US general population of alcohol dependent drinkers. Results highlight the value of treatment for mitigating the persistence of dependence among Type B alcoholics in the general population. Screening for markers of vulnerability to Type B dependence could be of clinical value for health care providers to determine appropriate intervention.

摘要

背景

本研究检验了A/B型酒精依赖在普通人群中的同时效度和预测效度——这是一种在临床人群中开发出来用以衡量依赖严重程度的类型学。

方法

数据取自全国酒精及相关疾病流行病学调查(NESARC)的第1波和第2波。样本包括1172名基线时酒精依赖的饮酒者,三年后对他们进行了再次访谈。使用潜在类别分析,通过复制原始A/B型类型学的变量得出A/B型分类。通过多变量线性回归和逻辑回归评估A/B型分类的预测效度。

结果

与巴伯最初的A/B型类型学一致的两类解决方案能够很好地拟合数据。与A型酒精依赖者相比,普通人群中的B型酒精依赖者有更高的酒精严重程度,以及更多共病的药物、精神和身体健康问题。在未接受治疗服务的情况下,B型饮酒者三年后酒精依赖的几率是其他人的两倍。在那些接受酒精治疗服务的人中,三年后B型分类可预测重度饮酒和药物依赖,但不能预测酒精依赖。

结论

研究结果表明,A/B型分类在美国酒精依赖饮酒者的普通人群中既具有普遍性又具有效度。结果凸显了治疗对于减轻普通人群中B型酒精依赖者依赖持续性情况的价值。筛查B型依赖易感性标志物可能对医疗保健提供者确定适当干预措施具有临床价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6367/4074591/17d1f5dd16ca/nihms-576822-f0001.jpg

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