Aslam Muhammad, Sial Ali Akbar
Department of Basic Medical Sciences, Faculty of Pharmacy, Ziauddin University, Karachi 75600, Pakistan.
Department of Pharmaceutics, Faculty of Pharmacy, Ziauddin University, Karachi 75600, Pakistan.
Adv Pharmacol Sci. 2014;2014:282698. doi: 10.1155/2014/282698. Epub 2014 Feb 4.
Cydonia oblonga Miller (quince) is regarded as a potent libido invigorator in Tib-e-Nabvi and Unani System of Medicine. This study was carried out to evaluate the aphrodisiac activity of the hydroalcoholic extract of the fruits of Cydonia oblonga Miller (quince) in Wistar rats. The extract was administered orally by gavage in the dose of 500 mg/kg and 800 mg/kg body weight per day as a single dose for 28 days. The observed parameters were mounting frequency, assessment of mating performance, and orientation activities towards females, towards the environment, and towards self. The results showed that after administration of the extract mounting frequency and the mating performance of the rats increased highly significantly (P < 0.01). The extract also influenced the behaviour of treated animals in comparison to nontreated rats in a remarkable manner, making them more attracted to females. These effects were observed in sexually active male Wistar rats.
榅桲(Cydonia oblonga Miller)在《希波克拉底医学》和尤纳尼医学体系中被视为一种强效的性欲增强剂。本研究旨在评估榅桲果实水醇提取物对Wistar大鼠的壮阳活性。提取物以每天500毫克/千克和800毫克/千克体重的剂量通过灌胃法口服,作为单剂量给药28天。观察的参数包括爬跨频率、交配性能评估以及对雌性、对环境和对自身的定向活动。结果表明,给予提取物后,大鼠的爬跨频率和交配性能显著提高(P < 0.01)。与未处理的大鼠相比,提取物还以显著方式影响了处理动物的行为,使它们对雌性更具吸引力。在性活跃的雄性Wistar大鼠中观察到了这些效果。