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本文引用的文献

1
Chapter 8: Idiopathic membranoproliferative glomerulonephritis.第8章:特发性膜增生性肾小球肾炎。
Kidney Int Suppl (2011). 2012 Jun;2(2):198-199. doi: 10.1038/kisup.2012.21.
2
Eculizumab therapy in a patient with dense-deposit disease associated with partial lipodystropy.依库珠单抗治疗一名与部分脂肪营养不良相关的致密沉积物病患者。
Pediatr Nephrol. 2014 Jul;29(7):1283-7. doi: 10.1007/s00467-013-2748-5. Epub 2014 Jan 26.
3
Rituximab fails where eculizumab restores renal function in C3nef-related DDD.在C3肾炎因子相关的致密物沉积病中,依库珠单抗可恢复肾功能,而利妥昔单抗则无效。
Pediatr Nephrol. 2014 Jun;29(6):1107-11. doi: 10.1007/s00467-013-2711-5. Epub 2014 Jan 10.
4
Seroconversion of hepatitis B envelope antigen by entecavir in a child with hepatitis B virus-related membranous nephropathy.恩替卡韦使一名乙型肝炎病毒相关性膜性肾病患儿的乙型肝炎e抗原发生血清学转换。
J Nippon Med Sch. 2013;80(5):387-95. doi: 10.1272/jnms.80.387.
5
C3 glomerulopathy: clinicopathologic features and predictors of outcome.C3肾小球病:临床病理特征及预后预测因素
Clin J Am Soc Nephrol. 2014 Jan;9(1):46-53. doi: 10.2215/CJN.04700513. Epub 2013 Oct 31.
6
A novel CFHR5 fusion protein causes C3 glomerulopathy in a family without Cypriot ancestry.一种新型CFHR5融合蛋白在一个没有塞浦路斯血统的家族中导致了C3肾小球病。
Kidney Int. 2014 Apr;85(4):933-7. doi: 10.1038/ki.2013.348. Epub 2013 Sep 25.
7
Complement factor H related proteins (CFHRs).补体因子 H 相关蛋白(CFHRs)。
Mol Immunol. 2013 Dec 15;56(3):170-80. doi: 10.1016/j.molimm.2013.06.001. Epub 2013 Jul 3.
8
Eculizumab and recurrent C3 glomerulonephritis.依库珠单抗与 C3 肾小球肾炎复发。
Pediatr Nephrol. 2013 Oct;28(10):1975-81. doi: 10.1007/s00467-013-2503-y. Epub 2013 May 22.
9
Membranoprolferative glomerulonephritis - mechanisms and treatment.膜增生性肾小球肾炎——发病机制与治疗
Contrib Nephrol. 2013;181:163-74. doi: 10.1159/000348635. Epub 2013 May 8.
10
Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome.DGKE 中的隐性突变导致非典型溶血尿毒综合征。
Nat Genet. 2013 May;45(5):531-6. doi: 10.1038/ng.2590. Epub 2013 Mar 31.

美国肾脏病学会临床病理会议

American Society of Nephrology clinical pathological conference.

作者信息

Meyers Kevin E, Liapis Helen, Atta Mohamed G

机构信息

The Children Hospital of Philadelphia and University of Pennsylvania, Philadelphia, Pennsylvania;, †Division of Anatomic and Molecular Pathology, Washington University School of Medicine, St. Louis, Missouri, ‡Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

出版信息

Clin J Am Soc Nephrol. 2014 Apr;9(4):818-28. doi: 10.2215/CJN.12481213. Epub 2014 Mar 20.

DOI:10.2215/CJN.12481213
PMID:24651072
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3974370/
Abstract

A 13-year-old girl presented with proteinuria and acute kidney failure. She was born at full term via cesarean delivery (due to nuchal cord), but there were no other prenatal or perinatal complications. In early childhood the patient had two hospitalizations at ages 4.5 and 9 years, respectively, the latter for pneumonia. She had no history of symptoms of kidney disease. She came to the hospital at age 12 years for routine bilateral molar extractions. She was treated with oral antibiotics and discharged after the procedure without complications. At age 13 years, 10 months after the molar extraction, she was seen by a pediatrician because of puffiness and increased BP. She had had respiratory symptoms 2 weeks before presentation. The pediatrician prescribed furosemide and amlodipine. A few days later, the patient returned to the pediatrician's office because of hand, ankle, and facial swelling and malaise. The pediatrician recommended hospitalization and the patient was admitted at this time.

摘要

一名13岁女孩出现蛋白尿和急性肾衰竭。她足月剖宫产出生(因脐带绕颈),但无其他产前或围产期并发症。幼儿期患者分别在4.5岁和9岁时住院两次,后者因肺炎。她无肾病症状史。12岁时她因常规双侧磨牙拔除前来医院。她接受了口服抗生素治疗,术后无并发症出院。13岁时,磨牙拔除10个月后,因面部浮肿和血压升高被儿科医生诊治。就诊前2周她有呼吸道症状。儿科医生开了呋塞米和氨氯地平。几天后,患者因手、脚踝和面部肿胀以及不适返回儿科医生办公室。儿科医生建议住院,患者此时入院。