Meyers Kevin E, Liapis Helen, Atta Mohamed G
The Children Hospital of Philadelphia and University of Pennsylvania, Philadelphia, Pennsylvania;, †Division of Anatomic and Molecular Pathology, Washington University School of Medicine, St. Louis, Missouri, ‡Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Clin J Am Soc Nephrol. 2014 Apr;9(4):818-28. doi: 10.2215/CJN.12481213. Epub 2014 Mar 20.
A 13-year-old girl presented with proteinuria and acute kidney failure. She was born at full term via cesarean delivery (due to nuchal cord), but there were no other prenatal or perinatal complications. In early childhood the patient had two hospitalizations at ages 4.5 and 9 years, respectively, the latter for pneumonia. She had no history of symptoms of kidney disease. She came to the hospital at age 12 years for routine bilateral molar extractions. She was treated with oral antibiotics and discharged after the procedure without complications. At age 13 years, 10 months after the molar extraction, she was seen by a pediatrician because of puffiness and increased BP. She had had respiratory symptoms 2 weeks before presentation. The pediatrician prescribed furosemide and amlodipine. A few days later, the patient returned to the pediatrician's office because of hand, ankle, and facial swelling and malaise. The pediatrician recommended hospitalization and the patient was admitted at this time.
一名13岁女孩出现蛋白尿和急性肾衰竭。她足月剖宫产出生(因脐带绕颈),但无其他产前或围产期并发症。幼儿期患者分别在4.5岁和9岁时住院两次,后者因肺炎。她无肾病症状史。12岁时她因常规双侧磨牙拔除前来医院。她接受了口服抗生素治疗,术后无并发症出院。13岁时,磨牙拔除10个月后,因面部浮肿和血压升高被儿科医生诊治。就诊前2周她有呼吸道症状。儿科医生开了呋塞米和氨氯地平。几天后,患者因手、脚踝和面部肿胀以及不适返回儿科医生办公室。儿科医生建议住院,患者此时入院。