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The expression of genes coding for positive acute-phase proteins in the reproductive tract of the female rat. High levels of ceruloplasmin mRNA in the uterus.

作者信息

Thomas T, Schreiber G

机构信息

Russell Grimwade School of Biochemistry, University of Melbourne, Parkville, VIC, Australia.

出版信息

FEBS Lett. 1989 Jan 30;243(2):381-4. doi: 10.1016/0014-5793(89)80166-8.

DOI:10.1016/0014-5793(89)80166-8
PMID:2465186
Abstract

High levels of ceruloplasmin mRNA were measured in the uterus of both pregnant and non-pregnant rats. No mRNA for alpha 2-macroglobulin and alpha 1-acid glycoprotein could be detected in the uterus in contrast to the high levels of those two mRNAs found in the decidua in the mid-gestation period. Synthesis of plasma proteins with a protective function in the decidua or uterus may be important in maintaining homeostasis at different stages of reproduction. In addition, ceruloplasmin synthesis by the uterus may be part of a system transporting copper to the fetus.

摘要

相似文献

1
The expression of genes coding for positive acute-phase proteins in the reproductive tract of the female rat. High levels of ceruloplasmin mRNA in the uterus.
FEBS Lett. 1989 Jan 30;243(2):381-4. doi: 10.1016/0014-5793(89)80166-8.
2
Distribution of alpha 2-macroglobulin and alpha 1-acid glycoprotein mRNA shows regional specialization in rat decidua.α2-巨球蛋白和α1-酸性糖蛋白mRNA在大鼠蜕膜中的分布呈现区域特异性。
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The development of rat alpha 2-macroglobulin. Studies in vivo and in cultured fetal rat hepatocytes.大鼠α2-巨球蛋白的发育。体内及培养的胎鼠肝细胞研究。
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6
The expression of alpha(1)-acid glycoprotein mRNA during rat development. High levels of expression in the decidua.大鼠发育过程中α(1)-酸性糖蛋白mRNA的表达。在蜕膜中表达水平较高。
J Biol Chem. 1989 Apr 5;264(10):5784-90.
7
Cell-specific expression of activin and its two binding proteins in the rat decidua: role of alpha 2-macroglobulin and follistatin.激活素及其两种结合蛋白在大鼠蜕膜中的细胞特异性表达:α2-巨球蛋白和卵泡抑素的作用
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Rat ceruloplasmin. Molecular cloning and gene expression in liver, choroid plexus, yolk sac, placenta, and testis.
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Differential nm23 gene expression at the fetal-maternal interface.胎儿-母体界面处nm23基因的差异表达。
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10
Alpha 2-macroglobulin expression in the mesometrial decidua and its regulation by decidual luteotropin and prolactin.α2-巨球蛋白在子宫系膜蜕膜中的表达及其受蜕膜促黄体素和催乳素的调节。
Endocrinology. 1992 Sep;131(3):1321-8. doi: 10.1210/endo.131.3.1380439.

引用本文的文献

1
Identification of pituitary adenylate cyclase-activating polypeptide1-38-binding factor in human plasma, as ceruloplasmin.在人血浆中鉴定出垂体腺苷酸环化酶激活多肽1-38结合因子为铜蓝蛋白。
Biochem J. 1999 Jul 15;341 ( Pt 2)(Pt 2):271-6.
2
Tissue-specific ceruloplasmin gene expression in the mammary gland.
Biochem J. 1991 Dec 15;280 ( Pt 3)(Pt 3):671-7. doi: 10.1042/bj2800671.
3
Caeruloplasmin biosynthesis by the human uterus.人子宫中铜蓝蛋白的生物合成。
Biochem J. 1992 Dec 1;288 ( Pt 2)(Pt 2):657-61. doi: 10.1042/bj2880657.