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凝血检查在溶血尿毒综合征诊断中的重要性及其治疗经验。

Importance of blood clotting tests in the diagnosis of haemolytic-uremic syndrome and experience with its treatment.

作者信息

Valnícek S, Dolezel J, Hrubanová J, Habancová M, Stejskal J

机构信息

Department of Clinical Haematology, Pediatric Teaching Hospital, Brno, CSSR.

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1988;115(3):371-6.

PMID:2465233
Abstract

More than half of 33 children with HUS were less than a year old, 90% less than five. A constant laboratory finding was the presence of FDP in the blood and urine, and of the remaining tests the presence of erythrocyte fragments. The absence of thrombocytopenia does not eliminate HUS. Antiplatelet treatment was given to 94% of children, heparin to 94%, thrombolysis to 27% Precise evaluation of treatment would require a controlled prospective multicentre study.

摘要

33例溶血尿毒综合征患儿中,半数以上年龄小于1岁,90%小于5岁。一项持续的实验室检查结果是血液和尿液中存在纤维蛋白降解产物(FDP),其余检查则显示存在红细胞碎片。血小板减少症的不存在并不能排除溶血尿毒综合征。94%的患儿接受了抗血小板治疗,94%接受了肝素治疗,27%接受了溶栓治疗。对治疗进行精确评估需要一项对照前瞻性多中心研究。

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