Zapff G, Scheibe I, Toursel W, Dekowski D, Richter H
Bezirksinstitut für Blutspende- und Transfusionswesen, Berlin.
Folia Haematol Int Mag Klin Morphol Blutforsch. 1988;115(5):755-67.
The cryopreservation of human platelets was carried out with a final glycerol concentration of 0.38-0.48 mol/l (3.5-4.5%). The in-vitro-recovery (total platelets, aggregation, 14C-5-HT-uptake, clot retraction, total ATP, morphology) was in the range of 35-93% in comparison with freshly prepared platelet concentrates. The platelet survival was investigated by 51chrom labeling and autologous transfusion. A survival rate of 42% and a mean survival of 79% in comparison with freshly prepared platelets is concentrates are the results. In spite of reduced viability the cryopreservation of platelets is invaluable for providing compatible platelets for alloimmunized patients.
