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1
Methadone, QTc prolongation and torsades de pointes: Current concepts, management and a hidden twist in the tale?
J Cardiovasc Dis Res. 2013 Dec;4(4):229-35. doi: 10.1016/j.jcdr.2013.10.001. Epub 2013 Nov 16.
2
Methadone maintenance, QTc and torsade de pointes: who needs an electrocardiogram and what is the prevalence of QTc prolongation?
Drug Alcohol Rev. 2011 Jul;30(4):388-96. doi: 10.1111/j.1465-3362.2010.00237.x. Epub 2010 Sep 6.
6
New Generation Antipsychotic Drugs and QTc Interval Prolongation.
Prim Care Companion J Clin Psychiatry. 2003 Oct;5(5):205-215. doi: 10.4088/pcc.v05n0504.
8
Torsades de pointes with methadone.
Prescrire Int. 2005 Apr;14(76):61-2.
9
Methadone, Metoclopramide and Metronidazole Interaction Causing Torsades de Pointes.
Clin Pract. 2021 Feb 7;11(1):101-105. doi: 10.3390/clinpract11010015.
10
Corrected QT Interval Prolongation in Hospitalized Pediatric Patients Receiving Methadone.
Pediatr Crit Care Med. 2018 Aug;19(8):e403-e408. doi: 10.1097/PCC.0000000000001601.

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1
Cardiovascular Complications Following Acute Methadone Poisoning in Patients with and Without a History of Long-term Methadone Use.
J Res Pharm Pract. 2024 Dec 23;13(2):58-64. doi: 10.4103/jrpp.jrpp_49_24. eCollection 2024 Apr-Jun.
4
One-year survey of methadone-induced cardiac complications.
Caspian J Intern Med. 2023 Winter;14(1):43-46. doi: 10.22088/cjim.14.1.43.
7
Restless Legs Syndrome: Contemporary Diagnosis and Treatment.
Neurotherapeutics. 2021 Jan;18(1):140-155. doi: 10.1007/s13311-021-01019-4. Epub 2021 Apr 20.
8
Polymorphic Ventricular Tachycardia Associated with High-Dose Methadone Use.
Case Rep Cardiol. 2020 Sep 23;2020:4504657. doi: 10.1155/2020/4504657. eCollection 2020.
9
Pharmacogenomics of methadone: a narrative review of the literature.
Pharmacogenomics. 2020 Aug;21(12):871-887. doi: 10.2217/pgs-2020-0040. Epub 2020 Jul 24.

本文引用的文献

1
A continuing black hole? The FDA boxed warning: an appeal to improve its clinical utility.
Clin Toxicol (Phila). 2011 Jul;49(6):443-7. doi: 10.3109/15563650.2011.564585. Epub 2011 May 18.
3
Methadone deaths: risk factors in pain and addicted populations.
J Gen Intern Med. 2010 Apr;25(4):305-9. doi: 10.1007/s11606-009-1225-0. Epub 2010 Jan 20.
4
QTc interval screening in methadone treatment.
Ann Intern Med. 2009 Mar 17;150(6):387-95. doi: 10.7326/0003-4819-150-6-200903170-00103. Epub 2009 Jan 19.
5
Methadone: to ECG or not to ECG...That is still the question.
J Pain Symptom Manage. 2008 Nov;36(5):545-52. doi: 10.1016/j.jpainsymman.2007.11.003. Epub 2008 Apr 28.
6
Role of implantable cardioverter-defibrillators in patients with methadone-induced long QT syndrome.
Am J Cardiol. 2008 Jan 15;101(2):209-11. doi: 10.1016/j.amjcard.2007.07.068.
7
QT-interval effects of methadone, levomethadyl, and buprenorphine in a randomized trial.
Arch Intern Med. 2007 Dec 10;167(22):2469-75. doi: 10.1001/archinte.167.22.2469.
8
Common genetic variation in KCNH2 is associated with QT interval duration: the Framingham Heart Study.
Circulation. 2007 Sep 4;116(10):1128-36. doi: 10.1161/CIRCULATIONAHA.107.710780. Epub 2007 Aug 20.
10
Further evidence of inherited long QT syndrome gene mutations in antiarrhythmic drug-associated torsades de pointes.
Heart Rhythm. 2007 May;4(5):603-7. doi: 10.1016/j.hrthm.2007.01.019. Epub 2007 Jan 18.

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