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各种儿科液体药物侵蚀潜力的评估:一项体外研究。

Evaluation of the Erosive Potential of Various Pediatric Liquid Medicaments: An in-vitro Study.

作者信息

Tupalli Abhinaya Reddy, Satish B, Shetty Bharath Raj, Battu Someshwar, Kumar J Phani, Nagaraju B

机构信息

Department of Pedodontics & Preventive Dentistry, Sri Sai College of Dental Surgery, Vikarabad, Andhra Pradesh, India.

Department of Prosthodontics, A B Shetty Dental College, Deralakatte, Mangalore, Karnataka, India.

出版信息

J Int Oral Health. 2014 Feb;6(1):59-65. Epub 2014 Feb 26.

Abstract

BACKGROUND

The present in-vitro study was a scanning electron microscope (SEM) study conducted in primary teeth in order to evaluate the erosive potential of ten commonly used pediatric liquid medications (PLMs).

MATERIALS & METHODS: 10 commonly used PLMs and 33 exfoliated or extracted primary teeth were collected. The 33 teeth were divided into two groups, the control group (n=3) and the study group (n=30). The endogenous pH of all the teeth was measured using a pH electrode meter. The control group teeth were immersed in artificial saliva for three different time intervals- 1 minute, 10 minutes and 8 hours. The study group teeth were also maintained for 1 minute, 10 minutes and 8 hours in various selected PLMs. The primary enamel surface (PES) changes were then observed under the SEM for all the teeth of both groups.

RESULTS

All the PLMs used in the study showed an erosive effect on the PES when viewed under SEM. Majority of the medications caused etched prism pattern followed by crater formation and sporadic rod ends in that order on PES.

CONCLUSION

There is a need to educate parents and professionals about the association between dental erosion and PLMs which predisposes to dental caries. How to cite the article: Tupalli AR, Satish B, Shetty BR, Battu S, Kumar JP, Nagaraju B. Evaluation of the Erosive Potential of Various Pediatric Liquid Medicaments: An In-vitro Study. J Int Oral Health 2014;6(1):59-65.

摘要

背景

本体外研究是一项在乳牙上进行的扫描电子显微镜(SEM)研究,目的是评估十种常用儿科液体药物(PLM)的侵蚀潜力。

材料与方法

收集了10种常用PLM和33颗脱落或拔除的乳牙。将这33颗牙齿分为两组,对照组(n = 3)和研究组(n = 30)。使用pH电极仪测量所有牙齿的内源性pH值。对照组牙齿在人工唾液中浸泡三个不同的时间间隔——1分钟、10分钟和8小时。研究组牙齿也在各种选定的PLM中保持1分钟、10分钟和8小时。然后在SEM下观察两组所有牙齿的牙釉质表面(PES)变化。

结果

在SEM下观察时,研究中使用的所有PLM均对PES显示出侵蚀作用。大多数药物在PES上依次导致蚀刻棱柱图案,随后是坑洼形成和散在的杆端。

结论

有必要对家长和专业人员进行关于牙齿侵蚀与PLM之间关联的教育,PLM易引发龋齿。如何引用本文:Tupalli AR, Satish B, Shetty BR, Battu S, Kumar JP, Nagaraju B. Evaluation of the Erosive Potential of Various Pediatric Liquid Medicaments: An In-vitro Study. J Int Oral Health 2014;6(1):59 - 65.

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