Tüzüner Tamer, Turgut Sedanur, Baygin Ozgul, Yilmaz Nagehan, Tuna Elif Bahar, Ozen Bugra
Faculty of Dentistry, Department of Pediatric Dentistry, Karadeniz Technical University, Trabzon, Turkey.
Faculty of Dentistry, Department of Prosthetic Dentistry, Karadeniz Technical University, Trabzon, Turkey.
Biomed Res Int. 2017;2017:9684193. doi: 10.1155/2017/9684193. Epub 2017 Jan 10.
. The chronic recommendation of pediatric drugs could exhibit erosive and cariogenic problems. . To evaluate the effects of different pediatric drugs on the color stability of various restorative materials. . Five specimens (1 mm × 3 mm) were prepared and immersed in ten different pediatric drugs and agitated every 8 hours daily for 2 min up to 1 week. Between immersion periods, the samples were stored in artificial saliva. After 1-week period, Δ values were calculated. Two-way ANOVA and Fisher's LSD test were used for statistical analysis at a level of < 0.05. . Δ values were only significantly influenced by restorative material factor ( < 0.001) and varied in the range of 2.08 and 6.55 units for all drugs/restorative materials. The highest Δ was found in Ferrosanol B-composite (6.55 ± 1.38) and the lowest one was found in Dolven-glass ionomer (2.08 ± 0.40) pairwise. The most prominent Δ value elevations were obtained in composite material compared to the compomer and/or glass ionomers in Macrol, Ferrosanol B, and Ventolin ( < 0.001; for all) and also for other drugs ( < 0.05). Dolven exhibited significantly higher values compared to Augmentin ( = 0.021), Macrol ( = 0.018), and Ventolin ( = 0.013) in compomer group. . The clinically perceptible color changes for tested composite/pediatric drug pairwise can be more problematic than compomer and glass ionomers in pediatric dentistry.
. 长期推荐使用儿科药物可能会出现腐蚀性和致龋问题。. 评估不同儿科药物对各种修复材料颜色稳定性的影响。. 制备五个样本（1毫米×3毫米），并将其浸入十种不同的儿科药物中，每天每8小时搅拌2分钟，持续1周。在浸泡期间，样本保存在人工唾液中。1周后，计算Δ值。使用双向方差分析和Fisher最小显著差异检验进行统计分析，显著性水平为<0.05。. Δ值仅受修复材料因素的显著影响（<0.001），所有药物/修复材料的Δ值范围在2.08至6.55单位之间。成对比较中，Ferrosanol B复合树脂的Δ值最高（6.55±1.38），Dolven玻璃离子水门汀的Δ值最低（2.08±0.40）。与复合体和/或玻璃离子水门汀相比，在Macrol、Ferrosanol B和Ventolin中，复合材料的Δ值升高最为显著（所有均<0.001），其他药物中也是如此（<0.05）。在复合体组中，Dolven与阿莫西林/克拉维酸（=0.021）、Macrol（=0.018）和Ventolin（=0.013）相比，表现出显著更高的值。. 在儿童牙科中，测试的复合材料/儿科药物成对组合的临床可察觉颜色变化可能比复合体和玻璃离子水门汀更成问题。
