纵隔多灶性骨结核和淋巴结炎在FDG-PET/CT上酷似恶性肿瘤：一例报告

Multifoci Bone Tuberculosis and Lymphadenitis in Mediastinum Mimics Malignancy on FDG-PET/CT: A Case Report.

作者信息

Alan Selçuk Nalan, Fenercioğlu Ayşen, Selçuk Hatem Hakan, Uluçay Cağatay, Yencilek Esin

机构信息

Yeditepe University Hospital, Department of Nuclear Medicine, İstanbul, Turkey.

Yeditepe University Hospital, Department of Family Medicine, İstanbul, Turkey.

出版信息

Mol Imaging Radionucl Ther. 2014 Feb;23(1):39-42. doi: 10.4274/Mirt.145. Epub 2014 Feb 5.

DOI:10.4274/Mirt.145

PMID:24653936

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3957972/

Abstract

UNLABELLED

Positron Emission Tomography with 2-deoxy-[F-18]-fluoro-D-glucose (FDG-PET) has become a reliable diagnostic tool in clinical practice similar to Magnetic Resonance (MR) imaging and Computed Tomography (CT). FDG-PET has especially been used to differentiate malignant from benign lesions, and for staging and follow- up malignant tumors. However, FDG-PET has some pitfalls in cancer screening and FDG tracer accumulates at sites of infection and inflammation. Bone tuberculosis may be confused with malignant tumors of bone and its metastases, and can accumulate focally increased FDG in active period. We present a 60-year-old woman with lytic bone lesions and mediastinal hypermetabolic foci, initially suspected to be malignant by means of FDG-PET and the other imaging modalities; however, bone biopsy confirmed the diagnosis of bone tuberculosis.

CONFLICT OF INTEREST

None declared.

摘要

未标注

正电子发射断层扫描术结合2-脱氧-[F-18]-氟-D-葡萄糖（FDG-PET）已成为临床实践中一种可靠的诊断工具，类似于磁共振（MR）成像和计算机断层扫描（CT）。FDG-PET尤其用于鉴别恶性病变与良性病变，以及对恶性肿瘤进行分期和随访。然而，FDG-PET在癌症筛查中有一些缺陷，并且FDG示踪剂会在感染和炎症部位积聚。骨结核可能会与骨恶性肿瘤及其转移灶相混淆，并且在活动期可局部积聚增加的FDG。我们报告一名60岁女性，有溶骨性骨病变和纵隔高代谢灶，最初通过FDG-PET及其他成像方式怀疑为恶性；然而，骨活检确诊为骨结核。