1 Department of Nuclear Medicine, 2 Department of Laboratory Medicine, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
Ann Transl Med. 2016 Feb;4(3):58. doi: 10.3978/j.issn.2305-5839.2016.01.14.
Castleman disease (CD) is a chronic lymphoproliferative disorder characterized by unexplained enlarged lymph nodes. According to lymph nodes distribution it contains two types of single-centric and multicentric (more than one site) disease. Multicentric Castleman disease (MCD) is rare, and shows unspecific manifestation with high misdiagnosis rate. Here we reported a case of MCD in a 43-year-old male. (18)F-FDG PET/CT imaging demonstrated higher FDG uptake in multiple lymph nodes and slightly FDG uptake in spleen and bone marrow. Right inguinal Lymph node biopsy was taken and the results confirmed CD.
卡斯尔曼病(CD)是一种慢性淋巴组织增生性疾病,其特征为原因不明的淋巴结肿大。根据淋巴结分布,它包含单中心型和多中心型(一个以上部位)两种类型。多中心卡斯尔曼病(MCD)较为罕见,表现为非特异性,误诊率高。我们在此报告一例 43 岁男性 MCD 病例。(18)F-FDG PET/CT 成像显示多个淋巴结摄取更高的 FDG,脾脏和骨髓摄取略高。取右侧腹股沟淋巴结活检,结果证实为 CD。