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韩国器官移植登记处的初步报告:国家肾脏移植数据的首份报告。

Initial report of the Korean Organ Transplant Registry: the first report of national kidney transplantation data.

作者信息

Ahn C, Koo T Y, Jeong J C, Kim M, Yang J, Lee J, Min S I, Lee J E, Kim M S, Kwon O J, Kim S J, Kim Y H, Kim Y H, Choi B S, Choi S J N, Lee D-H, Chung S Y, Cho W H, Kim Y S

机构信息

Transplantation Center, Seoul National University Hospital, Seoul, Korea.

Transplantation Center, Seoul National University Hospital, Seoul, Korea.

出版信息

Transplant Proc. 2014;46(2):425-30. doi: 10.1016/j.transproceed.2013.11.083.

DOI:10.1016/j.transproceed.2013.11.083
PMID:24655980
Abstract

PURPOSE

A national organ transplant registry is an indispensable organizational requirement for patient care, research, and planning. Even though the Korean Network for Organ Sharing (KONOS) has established a database for a waiting list, organ allocation, and incidence of organ transplantation since 2000, an integrated registry including post-transplantation data is needed for better understanding of organ transplantation. Recently, the Korean Society for Transplantation (KST) and the Korean Center for Disease Control (KCDC) designed a web-based organ transplant registry, named the Korean Organ Transplant Registry (KOTRY). As an initial project of KOTRY, we retrospectively analyzed kidney transplantations (KTs) performed in 2009 and 2010.

METHODS

A total of 2292 KTs (91.9%) from 46 hospitals (80.7%) were collected and analyzed. Ninety-five elements related to KT were selected and analyzed.

RESULTS

Proportions of male recipients and retransplantations were 58.4% and 7.1%, respectively. Even though glomerulonephritis was the most common cause of end-stage renal disease (ESRD) (28.4%), the number of diabetic nephropathy cases was increasing. The living donor (LD) to deceased donor (DD) ratio was 1.69:1. Because of a serious organ shortage in Korea, DD kidneys with a low initial estimated glomerular filtration rate (eGFR) of <45 mL/min/1.73 m(2) (21.2%) and expanded criteria donors (ECDs; 18.3%) are frequently used. Other noticeable findings are the increasing number of wife donors and ABO-incompatible (ABOi) transplants for O(+) recipients.

CONCLUSIONS

The epidemiological profile of transplantation is different from country to country. The number of organ transplantations in East Asian countries is rapidly growing, however, there are few epidemiological data about this region in the literature. With the establishment of KOTRY, it was possible to present the first nationwide epidemiological data of Korean KTs.

摘要

目的

国家器官移植登记系统是患者护理、研究和规划不可或缺的组织要求。尽管韩国器官共享网络(KONOS)自2000年以来已建立了等待名单、器官分配和器官移植发生率的数据库,但为了更好地了解器官移植,仍需要一个包括移植后数据的综合登记系统。最近,韩国移植学会(KST)和韩国疾病控制中心(KCDC)设计了一个基于网络的器官移植登记系统,名为韩国器官移植登记系统(KOTRY)。作为KOTRY的首个项目,我们对2009年和2010年进行的肾移植(KT)进行了回顾性分析。

方法

收集并分析了来自46家医院(80.7%)的2292例KT(91.9%)。选择并分析了95个与KT相关的要素。

结果

男性受者和再次移植的比例分别为58.4%和7.1%。尽管肾小球肾炎是终末期肾病(ESRD)最常见的病因(28.4%),但糖尿病肾病病例数正在增加。活体供者(LD)与尸体供者(DD)的比例为1.69:1。由于韩国器官严重短缺,初始估计肾小球滤过率(eGFR)<45 mL/min/1.73 m²(21.2%)的DD肾和扩大标准供者(ECD;18.3%)经常被使用。其他值得注意的发现是妻子供者的数量增加以及O(+)受者的ABO血型不相容(ABOi)移植。

结论

移植的流行病学特征因国家而异。东亚国家的器官移植数量正在迅速增长,然而,文献中关于该地区的流行病学数据很少。随着KOTRY的建立,有可能呈现韩国KT的首个全国性流行病学数据。

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