College of Chemistry, Xiangtan University, Xiangtan 411105, Hunan Province, PR China.
College of Chemistry, Xiangtan University, Xiangtan 411105, Hunan Province, PR China; Key Laboratory of Polymeric Materials & Application Technology of Hunan Province, Xiangtan University, Xiangtan 411105, Hunan Province, PR China; Key Laboratory of Advanced Functional Polymeric Materials of College of Hunan Province, Xiangtan University, Xiangtan 411105, Hunan Province, PR China.
Mater Sci Eng C Mater Biol Appl. 2014 May 1;38:292-8. doi: 10.1016/j.msec.2014.02.017. Epub 2014 Feb 20.
In this study, Au nanoparticles decorated graphene nanosheets were prepared using poly(vinylpyrrolidone) (PVP) covalently functionalized graphene oxide and chloroauric acid as template and Au precursor, respectively. Both the density and the size of Au nanoparticles deposited on the surface of graphene could be adjusted by the PVP grafting density. The graphene-Au hybrid nanosheets were then applied to fabricate a highly sensitive l-cysteine (L-CySH) electrochemical sensing platform. The cyclic voltammetry results showed that the modified glassy carbon electrode with graphene-Au hybrid nanosheets exhibited strong catalytic activity toward the electrooxidation of L-CySH. The current exhibited a widely linear response ranging from 0.1 to 24 μM with a low detection limit under the optimized conditions. The detection limit of L-CySH could reach as low as 20.5 nM (S/N=3). The enhanced electrochemical performance of the fabricated sensor was attributed to the combination of the excellent conductivity of graphene and strong catalytic property of uniform Au nanoparticles.
在这项研究中，使用聚（N-乙烯基吡咯烷酮）（PVP）共价功能化氧化石墨烯和氯金酸分别作为模板和 Au 前体，制备了 Au 纳米粒子修饰的石墨烯纳米片。通过 PVP 接枝密度，可以调节沉积在石墨烯表面的 Au 纳米粒子的密度和尺寸。然后，将石墨烯-Au 杂化纳米片应用于制备高灵敏度 l-半胱氨酸（L-CySH）电化学传感平台。循环伏安法结果表明，在优化条件下，具有石墨烯-Au 杂化纳米片的修饰玻碳电极对 L-CySH 的电氧化表现出很强的催化活性。电流在 0.1 至 24 μM 范围内表现出广泛的线性响应，检测限低。L-CySH 的检测限可低至 20.5 nM（S/N=3）。所制备传感器的增强电化学性能归因于石墨烯的优异导电性和均匀 Au 纳米粒子的强催化性能的结合。
