Virulence associated plasmid and R-plasmid curing in Yersinia enterocolitica by some tricyclic compounds.

The virulence plasmid which confers calcium-dependent growth in Yersinia enterocolitica and the R-plasmid of a Y. enterocolitica strain were eliminated by several, tricyclic psychopharmacons, e.g. promethazine, imipramine, and (+) and (-)-butaclamols.