Department of Mental Health and Psychiatry, Service of Psychiatric Specialties, University Hospitals of Geneva, Switzerland.
Department of Medical Genetic and Laboratories, Psychiatric Genetic Unit, University Hospitals of Geneva, Switzerland.
Psychiatry Res. 2014 Jun 30;217(1-2):107-14. doi: 10.1016/j.psychres.2014.03.006. Epub 2014 Mar 12.
Adult attention deficit hyperactivity disorder (ADHD) is frequently associated with borderline personality disorder (BPD). As both disorders share some core clinical features they are sometimes difficult to distinguish from one another. The present work aimed to investigate differences in the expression of impulsivity, anger and aggression, quality of life as well as the number and severity of the comorbidities between ADHD, BPD, comorbid BPD-ADHD and control subjects. ADHD and BPD-ADHD patients showed a higher level of impulsivity than BPD and control subjects. BPD-ADHD patients had higher levels of substance abuse/dependence and higher levels of aggression than the other groups. Comorbid BPD-ADHD patients showed high levels of impulsivity and aggression, a characteristic that should draw the attention of clinicians on the necessity of providing an accurate diagnosis. The question also arises as to whether they represent a distinct clinical subgroup with specific clinical characteristics, outcomes and vulnerability factors.
成人注意缺陷多动障碍（ADHD）常与边缘型人格障碍（BPD）相关。由于这两种障碍具有一些共同的核心临床特征，因此有时难以将它们区分开来。本研究旨在调查 ADHD、BPD、共病 BPD-ADHD 和对照组之间冲动、愤怒和攻击、生活质量以及合并症数量和严重程度的表达差异。ADHD 和 BPD-ADHD 患者的冲动水平高于 BPD 和对照组。BPD-ADHD 患者的物质滥用/依赖程度和攻击水平高于其他组。共病 BPD-ADHD 患者表现出较高的冲动性和攻击性，这一特征应引起临床医生的注意，需要进行准确的诊断。此外，还有一个问题，即他们是否代表一个具有特定临床特征、结果和易感性因素的独特临床亚组。
