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[子宫颈小细胞神经内分泌癌:6例报告及文献复习]

[Small cell neuroendocrine carcinoma of the uterine cervix: Report of six cases and a review of the literature].

作者信息

Bellefqih S, Khalil J, Mezouri I, Kebdani T, Benjaafar N

机构信息

Service de radiothérapie, Institut national d'oncologie, avenue Allal-El Fassi, 10100 Rabat, Maroc.

Service de radiothérapie, Institut national d'oncologie, avenue Allal-El Fassi, 10100 Rabat, Maroc.

出版信息

Cancer Radiother. 2014 Jun;18(3):201-7. doi: 10.1016/j.canrad.2014.01.003. Epub 2014 Mar 19.

Abstract

Neuroendocrine carcinoma is a rare and aggressive malignant tumour, mainly developing at the expense of the respiratory and of the digestive tract. Gynecological neuroendocrine tumours are rare and small cell neuroendocrine tumours of the uterine cervix represent 2% of cervical cancer. Given their rarity and the lack of randomized trials, the diagnostic and therapeutic management of these tumors is difficult and essentially based on that of pulmonary neuroendocrine tumours. Like the latter, and despite multimodality regimens, the prognosis of these tumours remains poor. Through this series, we report our experience in the management of these particular tumours while comparing our data with those of the literature.

摘要

神经内分泌癌是一种罕见且侵袭性强的恶性肿瘤,主要发生于呼吸道和消化道。妇科神经内分泌肿瘤较为罕见,宫颈小细胞神经内分泌肿瘤占宫颈癌的2%。鉴于其罕见性以及缺乏随机试验,这些肿瘤的诊断和治疗管理较为困难,基本上是基于肺神经内分泌肿瘤的管理方法。与后者一样,尽管采用了多模式治疗方案,这些肿瘤的预后仍然很差。通过本系列研究,我们报告了我们在管理这些特殊肿瘤方面的经验,并将我们的数据与文献数据进行了比较。

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