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意大利地中海地区当地海产品中甲基汞摄入量的个体估算值。

Individual methylmercury intake estimates from local seafood of the Mediterranean Sea, in Italy.

作者信息

Dellatte Elena, Brambilla Gianfranco, Miniero Roberto, Abete Maria Cesarina, Orletti Roberta, Chessa Giannina, Ubaldi Alessandro, Chiaravalle Eugenio, Tiso Micaela, Ferrari Angelo

机构信息

Istituto Superiore di Sanità, Toxicological Chemistry Unit, Viale Regina Elena 299, I-00161 Rome, Italy.

Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, I-10154 Turin, Italy.

出版信息

Regul Toxicol Pharmacol. 2014 Jun;69(1):105-12. doi: 10.1016/j.yrtph.2014.03.002. Epub 2014 Mar 19.

Abstract

A Seafood Frequency Questionnaire (SFQ) broken down in more than 42 items with 8-week coverage was interview-administered to 278 adults aged 19-82years (167 women, 98 in the reproductive age 19-45years, and 111 men), resident on the Italian Mediterranean shore and frequent buyer at local fish markets. Methylmercury (MeHg) intake on individual basis was estimated for a selected occurrence equal to the median value+Median Absolute Deviation (MAD) in each seafood species reported (conservative scenario). MeHg occurrence was derived from an extensive seafood database referred to years 2009-2011. Accounting for an average body weight of 62.2kg, 24.6% of women resulted overexposed with respect to the European Food Safety Authority (EFSA) Tolerable Weekly Intake (TWI) for MeHg of 1.3μg/kg bw, with a mean of 0.92μg/kg bw. In the vulnerable group aged 19-45years, 29.6% exceeded the TWI. Rather than the amount of seafood consumed, the seafood choice appears to be the main determinant of the MeHg intake. Risk awareness was reported in the 49% of SFQs. Uncertainties related to such estimates from questionnaires are discussed, in order to give adequate health recommendations without compromising seafood consumption in the Mediterranean region.

摘要

一份包含42个以上项目、涵盖8周时间的海鲜频率调查问卷(SFQ),通过访谈的方式对278名年龄在19至82岁的成年人(167名女性,其中98名处于19至45岁的生育年龄,111名男性)进行了调查,这些人居住在意大利地中海沿岸,且是当地鱼市的常客。针对每种报告的海鲜品种,以选定的等于中位数+中位数绝对偏差(MAD)的出现频率为基础,估算个体甲基汞(MeHg)摄入量(保守情况)。MeHg出现频率源自2009年至2011年的一个广泛的海鲜数据库。考虑到平均体重为62.2千克,24.6%的女性甲基汞摄入量超过了欧洲食品安全局(EFSA)规定的1.3微克/千克体重的甲基汞每周可耐受摄入量(TWI),平均摄入量为0.92微克/千克体重。在19至45岁的易受影响群体中,29.6%的人超过了TWI。海鲜选择似乎是甲基汞摄入量的主要决定因素,而非食用的海鲜量。49%的SFQ报告了风险意识。讨论了与问卷调查估计相关的不确定性,以便在不影响地中海地区海鲜消费的情况下给出适当的健康建议。

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