Bellini M J, Terry R M, Lewis F A
ENT Department, Leeds General Infirmary, UK.
Clin Otolaryngol Allied Sci. 1989 Feb;14(1):23-5. doi: 10.1111/j.1365-2273.1989.tb00332.x.
Four non-prescription cerumenolytic agents were acquired over the counter of a high-street chemist and evaluated along with Sodium Bicarbonate ear drops BP, olive oil, distilled water, and acetone in an in-vitro study. Sodium Bicarbonate ear-drops BP are used by the nurses in the department and are recommended in the British National Formulary as the most effective solution to soften cerumen prior to syringing. Acetone was included as an effective organic solvent. The test was performed in a water bath, controlled to match the temperature of the external auditory meatus. Disintegration of the cerumen was noted over a two-hour period. Substantial disintegration occurred with three products: Waxsol, Stores Own Brand, and distilled water.
从一家商业街药店的柜台购买了四种非处方耵聍溶解剂，并与碳酸氢钠滴耳液英国药典版、橄榄油、蒸馏水和丙酮一起在一项体外研究中进行评估。该科室的护士使用碳酸氢钠滴耳液英国药典版，并且英国国家处方集推荐其为在冲洗耵聍之前软化耵聍的最有效溶液。丙酮作为一种有效的有机溶剂被纳入研究。测试在水浴中进行，水浴温度控制在与外耳道温度相匹配。在两小时的时间段内观察耵聍的崩解情况。三种产品出现了大量崩解：Waxsol、自有品牌产品和蒸馏水。
