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用于环形黏膜切除术的创新磁环:初步研究

Innovative magnetic rings for circumferential mucosectomy: preliminary research.

作者信息

An Geng Shu, Huai Zhang Qing, Sheng Zhou, Min Zhang Shu, Wen Yang Jing, Ming Hao Dong, Xing Zhang Zuo

出版信息

Surg Today. 2015 Jan;45(1):78-82. doi: 10.1007/s00595-014-0878-4.

DOI:10.1007/s00595-014-0878-4
PMID:24658640
Abstract

PURPOSE

To improve the procedures used to treat prolapse and hemorrhoids, novel magnetic rings were invented to use in circumferential mucosectomies to avoid the disadvantages of stapling techniques.

METHODS

Thirty adult pigs were randomly divided into three groups: Group A (n = 10), which underwent circumferential mucosectomy with novel magnetic rings; Group B (n = 10), which underwent circumferential mucosectomy with conventional magnetic rings and Group C (n = 10), which underwent circumferential mucosectomy with a stapling technique.

RESULTS

All pigs underwent the operation successfully, and the mean length of the procedure was similar among the three groups (p > 0.05). There was no bleeding in Group A or Group B, while there was a mean blood loss of 78.32 ± 26.03 ml in Group C (p < 0.01). Three cases of anastomotic stenosis were found in Group C (3/10); two cases were found in Group B (2/10) and no anastomotic stenosis was found in Group A (0/10). The difference between groups A and C was statistically significant (p < 0.05). The cost for the magnetic rings in groups A and B was noticeably lower than that of the stapling techniques in Group C (20.12 ± 3.35 vs. 15.76 ± 2.92 vs. 550.16 ± 29.71 US dollars, p < 0.001). The magnetic rings in groups A and B were spontaneously discharged from the body with the necrotic tissues within 1-2 weeks (8.20 ± 2.73 vs. 9.31 ± 3.62 days, p > 0.05), avoiding the permanent implantation of staples in Group C. The anastomosis site in Group A showed a smoother and more rapid healing process than that in Group B or C.

CONCLUSIONS

The innovative magnetic rings we developed for circumferential mucosectomies provide a simple and novel surgical procedure for prolapse and hemorrhoids.

摘要

目的

为改进治疗直肠脱垂和痔疮的手术方法,发明了新型磁环用于环形黏膜切除术,以避免吻合器技术的缺点。

方法

将30只成年猪随机分为三组:A组(n = 10),采用新型磁环进行环形黏膜切除术;B组(n = 10),采用传统磁环进行环形黏膜切除术;C组(n = 10),采用吻合器技术进行环形黏膜切除术。

结果

所有猪均成功完成手术,三组手术平均时长相似(p > 0.05)。A组和B组均无出血,而C组平均失血量为78.32 ± 26.03 ml(p < 0.01)。C组发现3例吻合口狭窄(3/10);B组发现2例(2/10),A组未发现吻合口狭窄(0/10)。A组和C组之间的差异具有统计学意义(p < 0.05)。A组和B组磁环的成本明显低于C组吻合器技术的成本(分别为20.12 ± 3.35美元、15.76 ± 2.92美元和550.16 ± 29.71美元,p < 0.001)。A组和B组的磁环在1 - 2周内随坏死组织自行排出体外(分别为8.20 ± 2.73天和9.31 ± 3.62天,p > 0.05),避免了C组吻合器的永久植入。A组吻合口部位的愈合过程比B组或C组更平滑、更快。

结论

我们为环形黏膜切除术开发的创新磁环为直肠脱垂和痔疮提供了一种简单新颖的手术方法。

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Innovative magnetic rings for circumferential mucosectomy: preliminary research.用于环形黏膜切除术的创新磁环:初步研究
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Magnamosis II: Magnetic compression anastomosis for minimally invasive gastrojejunostomy and jejunojejunostomy.Ⅱ型麦格纳术:微创胃空肠吻合术和空肠空肠吻合术的磁压迫吻合术。
J Am Coll Surg. 2011 Jan;212(1):42-9. doi: 10.1016/j.jamcollsurg.2010.09.031.
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Smart Self-Assembling MagnetS for ENdoscopy (SAMSEN) for transoral endoscopic creation of immediate gastrojejunostomy (with video).智能自组装磁体用于内镜下经口即刻胃空肠吻合术(附视频)。
Gastrointest Endosc. 2011 Feb;73(2):353-9. doi: 10.1016/j.gie.2010.10.024. Epub 2010 Dec 22.
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Use of a metallic-wall stent in the magnet compression anastomosis technique for bile duct obstruction after liver transplantation.
金属壁支架在肝移植术后胆管梗阻磁压缩吻合技术中的应用。
Liver Transpl. 2008 Jan;14(1):118-20. doi: 10.1002/lt.21273.
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Compression gastrointestinal anastomosis.压迫性胃肠吻合术
Expert Rev Med Devices. 2007 Nov;4(6):821-8. doi: 10.1586/17434440.4.6.821.
5
Compression anastomoses revisited.再探压迫性吻合术。
J Am Coll Surg. 2005 Dec;201(6):965-71. doi: 10.1016/j.jamcollsurg.2005.06.255. Epub 2005 Sep 21.
6
Yamanouchi magnetic compression anastomosis for bilioenteric anastomotic stricture after living-donor liver transplantation.山之内磁性压迫吻合术治疗活体肝移植术后胆肠吻合口狭窄
J Vasc Interv Radiol. 2005 Sep;16(9):1263-7. doi: 10.1097/01.RVI.0000173280.56442.9E.
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Magnet compression anastomosis for bile duct stenosis after duct-to-duct biliary reconstruction in living donor liver transplantation.活体肝移植胆管对胆管重建术后胆管狭窄的磁压缩吻合术
Liver Transpl. 2005 Apr;11(4):473-5. doi: 10.1002/lt.20364.
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Side-to-side sutureless vascular anastomosis with magnets.使用磁体进行的端侧无缝合血管吻合术。
J Vasc Surg. 2004 Sep;40(3):505-11. doi: 10.1016/j.jvs.2004.05.026.
9
A novel technique of magnetic compression anastomosis for severe biliary stenosis.一种用于严重胆管狭窄的新型磁压缩吻合技术。
Gastrointest Endosc. 2003 Aug;58(2):283-7. doi: 10.1067/mge.2003.354.
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Early experiences with magnetic rings in resection of the distal colon.磁环在远端结肠切除术中的早期应用经验。
Neth J Surg. 1980;32(1):20-7.