Andreoli Laura, Alexandra Jean-François, Tesmoingt Chloé, Eerdekens Charlotte, Macrez Annick, Papo Thomas, Arnaud Philippe, Papy Emmanuelle
Drugs Aging. 2014 May;31(5):387-93. doi: 10.1007/s40266-014-0167-3.
Medication reconciliation has proved its effectiveness at improving drug-prescription safety. This study was undertaken to assess the impact of an intervention aimed at decreasing the discrepancies between a patient's usual treatment(s) and medications prescribed at admission.
Our study was conducted from November 2010 to May 2011. Discrepancies between home medication( s) and drugs prescribed to every patient aged C65 years, transferred from the Emergency Department and hospitalized in the Internal Medicine Unit, were analyzed.
During this 6-month period, 170 patients were prospectively included, with a total of 1,515 medicines reconciled. The unintentional discrepancy rate declined from 4.3 to 0.9 % after the intervention. The main sources of discrepancies concerned alimentary tract and metabolism (25.7 %), cardiovascular (24 %), and nervous system drugs (19.4 %).
The results of this study demonstrated that acquisition of patients' medication history is often incomplete or incorrect. Pharmacists seem to be especially well suited to help medical teams rectify this situation. However, the cost effectiveness of this intervention needs further assessment.
用药核对已证明其在提高药物处方安全性方面的有效性。本研究旨在评估一项旨在减少患者常规治疗与入院时所开药物之间差异的干预措施的影响。
我们的研究于2010年11月至2011年5月进行。分析了从急诊科转至内科病房住院的每位65岁及以上患者的家庭用药与所开药物之间的差异。
在这6个月期间,前瞻性纳入了170例患者,共核对了1515种药物。干预后无意差异率从4.3%降至0.9%。差异的主要来源涉及消化道和代谢(25.7%)、心血管(24%)和神经系统药物(19.4%)。
本研究结果表明,获取患者用药史往往不完整或不正确。药剂师似乎特别适合帮助医疗团队纠正这种情况。然而,这种干预措施的成本效益需要进一步评估。