利用光学微血管造影术对胶带剥离诱导的炎症性人体皮肤进行体内血流成像。
In vivo blood flow imaging of inflammatory human skin induced by tape stripping using optical microangiography.
作者信息
Wang Hequn, Baran Utku, Wang Ruikang K
机构信息
Department of Bioengineering, University of Washington, Seattle, WA, USA.
出版信息
J Biophotonics. 2015 Mar;8(3):265-72. doi: 10.1002/jbio.201400012. Epub 2014 Mar 21.
Abstract
Vasculature response is a hallmark for most inflammatory skin disorders. Tape stripping on human skin causes a minor inflammation which leads to changes in microvasculature. In this study, optical microangiography (OMAG), noninvasive volumetric microvasculature in vivo imaging method, has been used to track the vascular responses after tape stripping. Vessel density has been quantified and used to correlate with the degree of skin irritation. The proved capability of OMAG technique in visualizing the microvasculature network under inflamed skin condition can play an important role in clinical trials of treatment and diagnosis of inflammatory skin disorders.
摘要
血管反应是大多数炎症性皮肤病的一个标志。对人体皮肤进行胶带剥离会引发轻微炎症，进而导致微血管系统发生变化。在本研究中，光学微血管造影（OMAG）这种体内无创容积微血管成像方法，已被用于追踪胶带剥离后的血管反应。对血管密度进行了量化，并将其与皮肤刺激程度相关联。OMAG技术在炎症皮肤状况下可视化微血管网络的已证实能力，可在炎症性皮肤病的治疗和诊断临床试验中发挥重要作用。
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