*Ruiz Department of Ophthalmology and Visual Science, The University of Texas Medical School at Houston, Houston, TX; and †Robert Cizik Eye Clinic, Houston, TX.
Cornea. 2014 Nov;33(11):1240-4. doi: 10.1097/ICO.0000000000000254.
The aim of this study was to describe a novel surgical method for the sutureless placement of amniotic membrane on the bulbar and palpebral conjunctiva in the setting of ocular-involving acute Stevens-Johnson syndrome.
Within 6 days of an acute Stevens-Johnson episode, a 27-year-old male developed early symblepharon, despite aggressive lubrication and topical steroid therapy. He underwent symblepharon lysis and placement of an amniotic membrane wrapped around a symblepharon ring.
The patient maintained 20/20 vision in each eye with no recurrent symblepharon formation except for the temporal canthus (which was not covered with amniotic membrane).
Symblepharon rings covered in amniotic membrane provide a sutureless way to fixate amniotic membrane to the bulbar and palpebral conjunctiva. This gave very good anatomic and functional outcomes in a patient with acute Stevens-Johnson syndrome. Future research could be directed toward the development of a symblepharon ring that will be able to better protect the far temporal conjunctiva.
本研究旨在描述一种在伴有眼受累的急性 Stevens-Johnson 综合征患者中，在球结膜和睑结膜上无缝线放置羊膜的新手术方法。
在急性 Stevens-Johnson 综合征发作后 6 天内，一名 27 岁男性尽管进行了积极的润滑和局部皮质类固醇治疗，但仍出现早期睑球粘连。他接受了睑球粘连松解术，并在睑球粘连环上包裹了羊膜。
除了颞侧（未覆盖羊膜）外，患者双眼视力均保持 20/20，无复发性睑球粘连形成。
羊膜覆盖的睑球粘连环为固定羊膜至球结膜和睑结膜提供了一种无缝线的方法。这在患有急性 Stevens-Johnson 综合征的患者中获得了非常好的解剖和功能结果。未来的研究可以针对开发一种能够更好地保护远颞侧结膜的睑球粘连环。
