University of California, Beckman Laser Institute, 1002 Health Sciences Road East, Irvine, California 92612bOCT Medical Imaging Inc., 1002 Health Sciences Road East, Irvine, California 92612.
US Army Institute of Surgical Research, San Antonio Military Medical Center, Fort Sam Houston, San Antonio, Texas 78234.
J Biomed Opt. 2014 Mar;19(3):36018. doi: 10.1117/1.JBO.19.3.036018.
We report on the feasibility of using long-range swept-source optical coherence tomography (OCT) to detect airway changes following smoke inhalation in a sheep model. The long-range OCT system (with axial imaging range of 25 mm) and probe are capable of rapidly obtaining a series of high-resolution full cross-sectional images and three-dimensional reconstructions covering 20-cm length of tracheal and bronchial airways with airway diameter up to 25 mm, regardless of the position of the probe within the airway lumen. Measurements of airway thickness were performed at baseline and postinjury to show mucosal thickness changes following smoke inhalation.
我们报告了使用长距离扫频光学相干断层扫描（OCT）检测绵羊模型吸入烟雾后气道变化的可行性。长距离 OCT 系统（轴向成像范围为 25 毫米）和探头能够快速获得一系列高分辨率的全截面图像和三维重建，覆盖 20 厘米长的气管和支气管气道，气道直径可达 25 毫米，而与探头在气道腔内的位置无关。在基线和损伤后进行气道厚度测量，以显示吸入烟雾后黏膜厚度的变化。
