Inaloo Soroor, Haghbin Saideh
Associate Professor of Pediatric Neurology, Neonatal Research Center, Pediatrics Department, Shiraz University of Medical Sciences, Shiraz, Iran.
Fellow of Pediatric ICU, Assistant Professor of Pediatrics, Neonatal Research Center, Pediatrics Department, Shiraz University of Medical Sciences, Shiraz, Iran.
Iran J Child Neurol. 2013 Spring;7(2):1-10.
Multiple sclerosis (MS) is the most important immune-mediated demyelinated disease of human which is typically the disease of young adults. A total of 4% to 5% of MS population are pediatric. Pediatric MS is defined as the appearance of MS before the age of sixteen. About 80% of the pediatric cases and nearly all adolescent onset patients present with attacks typical to adult MS. Approximately 97% to 99% of the affected children have relapsing-remitting MS, while 85% to 95% of the adults experience such condition. MS in children is associated with more frequent and severe relapses. Treatment is the same as adults. We aimed to review the epidemiology, etiology, clinical manifestations, and treatment of MS in children.
多发性硬化症（MS）是人类最重要的免疫介导性脱髓鞘疾病，通常是年轻人易患的疾病。MS患者中4%至5%为儿童患者。儿童MS被定义为16岁之前出现的MS。约80%的儿童病例以及几乎所有青少年起病的患者都表现出与成人MS典型发作相同的症状。约97%至99%的患病儿童患有复发缓解型MS，而成人患者中这一比例为85%至95%。儿童MS的复发更为频繁和严重。其治疗方法与成人相同。我们旨在综述儿童MS的流行病学、病因、临床表现及治疗方法。
