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首次无诱因癫痫发作的处理方法——第一部分

Approach To The First Unprovoked Seizure- PART I.

作者信息

Ghofrani Mohammad

机构信息

Pediatric Neurology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran ; Pediatric Neurology Department, Mofid Children Hospital, Faculty of Medicin, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Iran J Child Neurol. 2013 Summer;7(3):1-5.

PMID:24665299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3943069/
Abstract

The approach to a child who has experienced a first unprovoked generalized tonic-clonic seizure is challenging and at the same time controversial. How to establish the diagnosis, ways and means of investigation and whether treatment is appropriate, are different aspects of this subject. In this writing the above mentioned matters are discussed.

摘要

对于首次发生无诱因全面性强直阵挛发作的儿童，处理起来颇具挑战性，同时也存在争议。如何确立诊断、检查的方式方法以及治疗是否恰当，都是该问题的不同方面。本文将对上述问题进行讨论。

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Approach To The First Unprovoked Seizure- PART I.首次无诱因癫痫发作的处理方法——第一部分
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Approach To The First Unprovoked Seizure- PART II.首次无诱因癫痫发作的处理方法 - 第二部分。
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本文引用的文献

1
Practice parameter: treatment of the child with a first unprovoked seizure: Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society.实践参数：首次无诱因癫痫发作儿童的治疗：美国神经病学学会质量标准小组委员会及儿童神经病学学会实践委员会报告
Neurology. 2003 Jan 28;60(2):166-75. doi: 10.1212/01.wnl.0000033622.27961.b6.
2
Death in children with epilepsy: a population-based study.
Lancet. 2002 Jun 1;359(9321):1891-5. doi: 10.1016/S0140-6736(02)08779-2.
3
Sudden unexplained death in children with epilepsy.癫痫患儿不明原因猝死。
Neurology. 2001 Aug 14;57(3):430-4. doi: 10.1212/wnl.57.3.430.
4
Mortality risk in children with epilepsy: the Dutch study of epilepsy in childhood.
Pediatrics. 2001 Jun;107(6):1259-63. doi: 10.1542/peds.107.6.1259.
5
Neuroimaging abnormalities in children with an apparent first unprovoked seizure.首次出现不明原因癫痫发作的儿童的神经影像学异常
Epilepsy Res. 2001 Mar;43(3):261-9. doi: 10.1016/s0920-1211(00)00206-0.
6
Practice parameter: evaluating a first nonfebrile seizure in children: report of the quality standards subcommittee of the American Academy of Neurology, The Child Neurology Society, and The American Epilepsy Society.实践参数：评估儿童首次非热性惊厥：美国神经病学学会、儿童神经病学会和美国癫痫学会质量标准小组委员会报告
Neurology. 2000 Sep 12;55(5):616-23. doi: 10.1212/wnl.55.5.616.
7
Effects of neonatal seizures on subsequent seizure-induced brain injury.新生儿惊厥对随后惊厥所致脑损伤的影响。
Neurology. 1999 Nov 10;53(8):1754-61. doi: 10.1212/wnl.53.8.1754.
8
Febrile seizures in the developing brain result in persistent modification of neuronal excitability in limbic circuits.发育中的大脑发生热性惊厥会导致边缘回路神经元兴奋性的持续改变。
Nat Med. 1999 Aug;5(8):888-94. doi: 10.1038/11330.
9
Epileptology of the first-seizure presentation: a clinical, electroencephalographic, and magnetic resonance imaging study of 300 consecutive patients.首次癫痫发作表现的癫痫学：对300例连续患者的临床、脑电图和磁共振成像研究
Lancet. 1998 Sep 26;352(9133):1007-11. doi: 10.1016/S0140-6736(98)03543-0.
10
Recurrent seizures in the developing brain are not harmful.发育中的大脑中反复出现的癫痫发作并无危害。
Epilepsia. 1997 Jun;38(6):735-7. doi: 10.1111/j.1528-1157.1997.tb01245.x.