Juraska J M, Fitch J M, Washburne D L
Department of Psychology, University of Illinois, Champaign 61820.
Brain Res. 1989 Feb 6;479(1):115-9. doi: 10.1016/0006-8993(89)91341-3.
Sex differences in the dendritic structure of hippocampal CA3 pyramidal neurons were studied in Golgi-stained tissue from hooded rats that had been raised in either a relatively complex or an isolated environment from weaning for one month. Pyramidal neurons were sampled from both the short-shaft and long-shaft neuron categories as described by Fitch et al. The pattern of sex differences varies in different parts of the apical dendritic tree. In the apical tree proximal to the soma, females had more dendritic material than males. This pattern was attributable to the sex differences in the short-shaft neurons of rats from the more complex environment. The direction of sex differences was reversed in the distal apical dendritic tree where males had more dendritic material than females. As in the proximal dendritic tree, this pattern of sex differences stemmed from the short-shaft neurons of rats from the more complex environment. There were no sex differences in the basilar dendritic tree. Thus sex differences in the pyramidal neurons of hippocampal area CA3 vary with the portion of the dendritic tree examined, the type of pyramidal neuron, and the rearing environment of the animal.
在经过高尔基染色的有帽大鼠组织中，研究了海马CA3锥体神经元树突结构的性别差异。这些大鼠从断奶起在相对复杂或隔离的环境中饲养了一个月。如菲奇等人所述，从短轴突和长轴突神经元类别中选取锥体神经元。顶端树突的不同部分，性别差异模式各不相同。在靠近胞体的顶端树突中，雌性比雄性有更多的树突物质。这种模式归因于来自更复杂环境的大鼠短轴突神经元中的性别差异。在顶端树突远端，性别差异的方向相反，雄性比雌性有更多的树突物质。与近端树突一样，这种性别差异模式源于来自更复杂环境的大鼠短轴突神经元。基底树突中没有性别差异。因此，海马区CA3锥体神经元的性别差异随所检查的树突部分、锥体神经元类型以及动物的饲养环境而变化。
