Norgren R B, Lehman M N
Department of Anatomy and Cell Biology, University of Cincinnati, College of Medicine, OH 45267-0521.
Brain Res. 1989 Feb 13;479(2):374-8. doi: 10.1016/0006-8993(89)91644-2.
Immunocytochemistry was used to identify infected cells after injection of Herpes simplex virus (HSV) into the superior colliculus, hypothalamus and optic chiasm. Ganglion cells of the retina were labeled in a pattern consistent with known projections to retinorecipient nuclei. Cells of both the inner and outer nuclear layer were labeled. If this represents retrograde transneuronal transport, then HSV may provide an important tool for studying the neuronal circuitry of the retina.
在将单纯疱疹病毒（HSV）注入上丘、下丘脑和视交叉后，采用免疫细胞化学方法鉴定感染细胞。视网膜神经节细胞的标记模式与已知的向视网膜接受核的投射一致。内核层和外核层的细胞均被标记。如果这代表逆行跨神经元运输，那么HSV可能为研究视网膜的神经回路提供一个重要工具。
