Staples M, Graham R M A, Jennison A V, Ariotti L, Hicks V, Cook H, Krause V, Giele C, Smith H V
Public Health Microbiology, Communicable Disease, Forensic and Scientific Services, Department of Health, Queensland,Australia.
Centre for Disease Control, Department of Health, Northern Territory,Australia.
Epidemiol Infect. 2015 Jan;143(2):325-33. doi: 10.1017/S0950268814000648. Epub 2014 Mar 25.
Serotype 1 Streptococcus pneumoniae is a cause of invasive pneumococcal disease (IPD) worldwide and has been associated with IPD outbreaks, while carriage is rarely detected in healthy adults or children. This study details an Australian multi-state and territory outbreak of serotype 1 S. pneumoniae IPD between 2010 and 2012. Molecular characterization demonstrated the outbreak was largely due to the clonal expansion of sequence type 306, MLVA type 261 S. pneumoniae serotype 1.
1型肺炎链球菌是全球侵袭性肺炎球菌疾病(IPD)的一个病因,且与IPD暴发有关,而在健康成人或儿童中很少检测到其携带情况。本研究详细介绍了2010年至2012年澳大利亚多个州和地区发生的1型肺炎链球菌IPD暴发。分子特征分析表明,此次暴发主要是由于序列型306、多重可变数目串联重复序列分析(MLVA)型261的1型肺炎链球菌的克隆性扩增。