Richter J M, Hilgenberg A D, Christensen M R, Logan D, Mathisen D J, Schapiro R H, Kelsey P B, Grillo H C
Medical Service (Gastrointestinal Unit), Massachusetts General Hospital, Boston 02114.
Gastrointest Endosc. 1988 Nov-Dec;34(6):454-8. doi: 10.1016/s0016-5107(88)71433-9.
To investigate the efficacy of alternative endoscopic palliative therapies for obstructive esophagogastric malignancy, the experience of 53 patients treated between 1979 and 1986 was analyzed. Forty-seven patients had placement of intraesophageal prostheses. Ten patients had prostheses placed after neodymium:YAG laser therapy. In four of these patients, prosthesis placement was planned as part of the initial therapy. Twelve patients initially received laser therapy. In six, recurrent tumor was treated with intraesophageal prostheses 3 to 24 weeks after laser treatment. Comparing neodymium:YAG laser therapy to placement of the prosthesis, both techniques provided similar improvement in dysphagia. Patients receiving prostheses required less additional treatment for dysphagia. Life table analysis comparing survival rates from diagnosis to death showed no difference. The palliation provided by prostheses and neodymium:YAG laser appears to be quite similar; however, the prosthesis seems to be more lasting and require fewer resources.
为研究替代内镜姑息治疗对梗阻性食管胃恶性肿瘤的疗效，分析了1979年至1986年间接受治疗的53例患者的经验。47例患者放置了食管内假体。10例患者在钕:钇铝石榴石激光治疗后放置了假体。其中4例患者，假体放置被规划为初始治疗的一部分。12例患者最初接受了激光治疗。6例患者在激光治疗后3至24周，复发性肿瘤采用食管内假体治疗。将钕:钇铝石榴石激光治疗与假体放置进行比较，两种技术在吞咽困难改善方面相似。接受假体治疗的患者因吞咽困难所需的额外治疗较少。比较从诊断到死亡的生存率的生命表分析显示无差异。假体和钕:钇铝石榴石激光提供的姑息治疗似乎非常相似；然而，假体似乎更持久且所需资源更少。
