小鼠L1210白血病的细胞化学特征

Cytochemical characterization of mouse L1210 leukemia.

作者信息

Kawiak J, Skórski T, Ciechanowicz A, Zylińska M, Seidel H J, Kawalec M, Gnatowski B, Czarnomska A

机构信息

Department of Cytophysiology, Medical Center of Postgraduate Education, Warsaw, Poland.

出版信息

Immunol Invest. 1988 Aug-Oct;17(6-7):543-50. doi: 10.3109/08820138809030587.

DOI:10.3109/08820138809030587

Abstract

Mouse lymphatic leukemia L1210 cells were characterized with polyclonal and monoclonal antibodies and lectins. The cells were found to have the phenotype IgG-, Thy-1.2-, Lyt-1-, Lyt-2-, asialo-GM1-, TL-, I-Ad-, IL-2R+, peanut agglutinin+, and Helix pomatia lectin +/-. They retained expression of H-2Kd and H-2Dd. Thus, these cells resemble "null" cells.

摘要

用多克隆抗体、单克隆抗体和凝集素对小鼠淋巴白血病L1210细胞进行了表征。发现这些细胞具有IgG-、Thy-1.2-、Lyt-1-、Lyt-2-、脱唾液酸GM1-、TL-、I-Ad-、IL-2R+、花生凝集素+和苹果蜗牛凝集素+/-的表型。它们保留了H-2Kd和H-2Dd的表达。因此，这些细胞类似于“裸”细胞。

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