蛙IgG中对小鼠组织具有亲和力的一种正常成分。
A normal component in ribbit IgG with affinity for mouse tissues.
作者信息
Witz I, Yagi Y, Pressman D
出版信息
Immunology. 1968 Nov;15(5):765-72.
Abstract
A part of the IgG from normal rabbit serum has been isolated which shows specificity of reactio when compared with the whole of rabbit serum IgG. When it is injected intravenously into mice bearing the L1210 leukaemia it has been found to be fixed in spleens to a much higher degree than is whole IgG. It is also fixed selectively on the sediments of L1210 cells. Some of this particular component cross-reacts well with other mouse tissues, while the rest shows an appreciable specificity for the L1210 cells.
摘要
已从正常兔血清中分离出一部分免疫球蛋白G（IgG），与兔血清中的全IgG相比，它表现出反应特异性。当将其静脉注射到患有L1210白血病的小鼠体内时，发现它在脾脏中的固定程度比全IgG高得多。它还选择性地固定在L1210细胞的沉淀物上。这种特殊成分中的一些与其他小鼠组织有良好的交叉反应，而其余部分则对L1210细胞表现出明显的特异性。
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