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体外受精-胚胎移植期间竖琴疗法的随机试验。

Randomized trial of harp therapy during in vitro fertilization-embryo transfer.

作者信息

Murphy Erin M, Nichols Jennifer, Somkuti Steve G, Sobel Michael, Braverman Andrea, Barmat Larry I

机构信息

Abington Reproductive Medicine, Abington Memorial Hospital, Abington, PA, USA.

出版信息

J Evid Based Complementary Altern Med. 2014 Apr;19(2):93-8. doi: 10.1177/2156587213514054. Epub 2013 Dec 18.

DOI:10.1177/2156587213514054
PMID:24668261
Abstract

OBJECTIVE

This study evaluated whether harp therapy reduces levels of stress and improves clinical outcomes in patients undergoing embryo transfer.

DESIGN

This prospective randomized trial enrolled 181 women undergoing embryo transfer, who were randomized to harp therapy during embryo transfer or standard treatment. Patients underwent standardized psychological testing and physiologic assessment of stress.

SETTING

The study was conducted in a reproductive medicine practice.

RESULTS

No statistically significant differences were found in the heart and respiratory rates, nor was there a significant difference in event-based anxiety at baseline. Harp therapy had a significantly larger decrease in state anxiety from pre- to post-embryo transfer. Clinical pregnancy was 53% versus 48% for the harp therapy and standard treatment groups, respectively.

CONCLUSION

Harp therapy decreases state, or event-based, anxiety, significantly lowering state scores posttransfer and having a positive effect on acute levels of stress. There was an increased pregnancy rate, but larger sample sizes are needed to evaluate whether harp therapy has an effect on clinical outcomes.

摘要

目的

本研究评估竖琴疗法是否能降低接受胚胎移植患者的压力水平并改善临床结局。

设计

这项前瞻性随机试验纳入了181名接受胚胎移植的女性,她们在胚胎移植期间被随机分为接受竖琴疗法或标准治疗。患者接受了标准化的心理测试和压力生理评估。

地点

该研究在一家生殖医学诊所进行。

结果

在心率和呼吸频率方面未发现统计学上的显著差异,基线时基于事件的焦虑也无显著差异。从胚胎移植前到移植后,竖琴疗法使状态焦虑的降低幅度显著更大。竖琴疗法组和标准治疗组的临床妊娠率分别为53%和48%。

结论

竖琴疗法可降低状态焦虑或基于事件的焦虑,显著降低移植后的状态评分,并对急性压力水平产生积极影响。妊娠率有所提高,但需要更大的样本量来评估竖琴疗法是否对临床结局有影响。

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