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音乐疗法对接受体外受精-胚胎移植女性焦虑水平及妊娠率的影响:一项随机对照试验。

Effect of music therapy on the anxiety levels and pregnancy rate of women undergoing in vitro fertilization-embryo transfer: A randomized controlled trial.

作者信息

Aba Yilda Arzu, Avci Dilek, Guzel Yilmaz, Ozcelik Semanur Kumral, Gurtekin Basak

机构信息

Bandirma Onyedi Eylul University Faculty of Health Sciences, Department of Nursing, Balikesir, Turkey.

Bandirma Onyedi Eylul University Faculty of Health Sciences, Department of Nursing, Balikesir, Turkey.

出版信息

Appl Nurs Res. 2017 Aug;36:19-24. doi: 10.1016/j.apnr.2017.05.005. Epub 2017 May 22.

Abstract

PURPOSE

The aim of this study was to determine the effect of music therapy on the anxiety levels and pregnancy rates of women who underwent in vitro fertilization-embryo transfer.

METHODS

This prospective randomized controlled trial was conducted with 186 infertile women who presented to the In Vitro Fertilization Unit at the American Hospital in Turkey between April 2015 and April 2016. The infertile women who met the inclusion criteria were assigned to the music therapy group or the standard therapy group through block randomization. The study data were collected using the Personal Information Form, and State-Trait Anxiety Inventory. Early treatment success was determined by serum beta human chorionic gonadotrophin levels seven or ten days after the luteal day zero. For the analysis, descriptive statistics, chi-square test, Fisher's exact test, independent sample t-test were used.

RESULTS

After the embryo transfer, the mean state anxiety scores decreased in both groups, and the mean trait anxiety score decreased in the music therapy group; however, the difference was not statistically significant (p>0.05). Clinical pregnancy rates did not differ between the music (48.3%) and standard (46.4%) therapy groups.

CONCLUSION

After the two sessions of music therapy, state and trait anxiety levels decreased and pregnancy rates increased, but the difference was not significant. Therefore, larger sample sizes and more sessions are needed to evaluate whether music therapy has an effect on clinical outcomes.

摘要

目的

本研究旨在确定音乐疗法对接受体外受精-胚胎移植的女性焦虑水平和妊娠率的影响。

方法

本前瞻性随机对照试验对2015年4月至2016年4月期间在土耳其美国医院体外受精科就诊的186名不孕女性进行。符合纳入标准的不孕女性通过区组随机化被分配到音乐治疗组或标准治疗组。研究数据通过个人信息表和状态-特质焦虑量表收集。早期治疗成功通过黄体期第0天7或10天后的血清β人绒毛膜促性腺激素水平来确定。分析时采用描述性统计、卡方检验、Fisher精确检验、独立样本t检验。

结果

胚胎移植后,两组的平均状态焦虑评分均下降,音乐治疗组的平均特质焦虑评分下降;然而,差异无统计学意义(p>0.05)。音乐治疗组(48.3%)和标准治疗组(46.4%)的临床妊娠率无差异。

结论

经过两期音乐治疗后,状态和特质焦虑水平下降,妊娠率上升,但差异不显著。因此,需要更大的样本量和更多的治疗期来评估音乐疗法是否对临床结局有影响。

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