为什么大脑自动调节的神经控制如此具有争议性？
Why is the neural control of cerebral autoregulation so controversial?
作者信息
Ainslie Philip N, Brassard Patrice
机构信息
Center for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia - Okanagan Kelowna, British Columbia Canada.
Department of Kinesiology, Faculty of Medicine, Université Laval Québec Canada ; Research Center of the Institut Universitaire de Cardiologie et de Pneumologie de Québec Québec Canada.
出版信息
F1000Prime Rep. 2014 Mar 3;6:14. doi: 10.12703/P6-14. eCollection 2014.
Abstract
Cerebral autoregulation refers to the mechanisms that act to keep cerebral blood flow (CBF) constant during changes in blood pressure. The mechanisms of cerebral autoregulation, especially in humans, are poorly understood but are undoubtedly multifactorial and likely reflect many redundant pathways that potentially differ between species. Whether sympathetic nervous activity influences CBF and/or cerebral autoregulation in humans remains controversial. Following a brief introduction to cerebral autoregulation, this review highlights the likely reasons behind the controversy of the neural control of cerebral autoregulation. Finally, suggestions are provided for further studies to improve the understanding of the neural control of CBF regulation.
摘要
脑自动调节是指在血压变化期间使脑血流量（CBF）保持恒定的机制。脑自动调节的机制，尤其是在人类中，目前了解甚少，但无疑是多因素的，并且可能反映了许多在不同物种之间可能存在差异的冗余途径。交感神经活动是否影响人类的脑血流量和/或脑自动调节仍存在争议。在对脑自动调节进行简要介绍之后，本综述重点强调了脑自动调节神经控制争议背后的可能原因。最后，为进一步研究提供了建议，以增进对脑血流量调节神经控制的理解。
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