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产科出血风险评估的实施:对其对输血前检测及出血结局影响的验证与评估

Implementation of an obstetric hemorrhage risk assessment: validation and evaluation of its impact on pretransfusion testing and hemorrhage outcomes.

作者信息

Wu Erica, Jolley Jennifer A, Hargrove Brooke A, Caughey Aaron B, Chung Judith H

机构信息

Department of Obstetrics and Gynecology, University of California , Irvine, Orange, CA , USA .

出版信息

J Matern Fetal Neonatal Med. 2015 Jan;28(1):71-6. doi: 10.3109/14767058.2014.905532. Epub 2014 Apr 9.

DOI:10.3109/14767058.2014.905532
PMID:24670202
Abstract

OBJECTIVE

To evaluate the impact of an obstetric hemorrhage risk assessment on pretransfusion testing and hemorrhage outcomes at a tertiary care, academic medical center.

METHODS

A retrospective cohort study was performed among women delivering neonates≥24 weeks from 2009 to 2011. Demographics, pretransfusion testing rates and hemorrhage outcomes were compared between those delivering before and after implementation of the risk assessment. Multivariable analyses were used to determine predictors of postpartum hemorrhage and transfusion.

RESULTS

There were 1388 women delivering before and 2121 women delivering after implementation of the risk assessment. More pretransfusion testing occurred after the assessment was initiated (22.8% versus 15.0%). Those who were considered high-risk were more likely to experience hemorrhage outcomes. In multivariable analyses, physician ordering practice in the pre-risk assessment period was a better prognosticator of both postpartum hemorrhage (aOR 9.98, 95% CI 5.02-19.82) and transfusion (aOR 31.14, 95% CI 14.97-64.82) than completion of a cross-match after implementation of the risk assessment (postpartum hemorrhage: aOR 2.10, 95% CI 1.20-3.66, transfusion: aOR 6.31, 95% CI 3.34-11.94).

CONCLUSIONS

Pre-risk assessment practice may be better at identifying those in need of blood transfusion, strictly due to the necessity for pretransfusion orders for transfusion to occur. In contrast, the obstetric hemorrhage risk assessment accurately predicted those who were more likely to experience hemorrhage outcomes. Optimal utilization of the risk assessment has yet to be determined.

摘要

目的

评估产科出血风险评估对一家三级医疗学术医学中心输血前检测及出血结局的影响。

方法

对2009年至2011年分娩孕周≥24周新生儿的女性进行一项回顾性队列研究。比较实施风险评估前后分娩女性的人口统计学特征、输血前检测率及出血结局。采用多变量分析确定产后出血和输血的预测因素。

结果

实施风险评估前有1388名女性分娩,实施后有2121名女性分娩。开始评估后进行输血前检测的情况增多(22.8%对15.0%)。被认为高危的女性更有可能出现出血结局。在多变量分析中,风险评估前时期医生的医嘱开具行为比风险评估实施后交叉配血的完成情况更能预测产后出血(调整后比值比[aOR]9.98,95%置信区间[CI]5.02 - 19.82)和输血(aOR 31.14,95% CI 14.97 - 64.82)(产后出血:aOR 2.10,95% CI 1.20 - 3.66;输血:aOR 6.31,95% CI 3.34 - 11.94)。

结论

风险评估前的实践可能在识别需要输血的患者方面表现更佳,这完全是由于输血需要输血前医嘱。相比之下,产科出血风险评估准确预测了那些更有可能出现出血结局的患者。风险评估的最佳利用方式尚未确定。

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