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[防腐剂活性指数]

[An index of the activity of antiseptics].

作者信息

Krasnil'nikov A P, Adarchenko A A

出版信息

Lab Delo. 1989(2):63-6.

PMID:2467067
Abstract

A new parameter is suggested: the antiseptic activity index (AAI), representing a ratio of the antiseptic concentration recommended for practice to its minimal suppressing concentration (MSC) for a certain bacterial strain or X + 2S MSC (the mean arithmetic value with two sigmas) for a population, species, or group of closely related species. This index has been determined in extrahospital and hospital strains of Staphylococcus aureus (342 strains), Pseudomonas aeruginosa (277 strains), and Enterobacteriaceae (500 strains). AAI gives a quantitative characterization of the antiseptic activity and of bacterial sensitivity to antiseptics, it is recommended for practical therapeutic and prophylactic antiseptics.

摘要

建议采用一个新参数

防腐活性指数(AAI),它表示实际推荐的防腐剂浓度与其对某一细菌菌株的最小抑制浓度(MSC)之比,或对于一个种群、物种或密切相关物种组而言,与其X + 2S MSC(两个标准差的算术平均值)之比。该指数已在医院外和医院的金黄色葡萄球菌菌株(342株)、铜绿假单胞菌菌株(277株)和肠杆菌科菌株(500株)中测定。AAI对防腐剂活性和细菌对防腐剂的敏感性进行了定量表征,推荐用于实际治疗和预防性防腐剂。

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