Liu Song, He Jian, Guan Wenxian, Li Qiang, Zhou Zhuping, Yu Haiping, Bao Shanhua, Zhou Zhengyang
Department of Radiology, The Affiliated Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China.
Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Mar;17(3):245-9.
To compare the accuracy of CT and MR including diffusion-weighted imaging(DWI) in preoperative diagnosis and T staging of gastric cancer.
Forty-one patients with gastric cancers proved by gastroscopy biopsy from November 2011 to August 2012 were prospectively enrolled. They underwent contrast enhanced CT and MR imaging (including DWI, T2 weighted and dynamic enhanced imaging) preoperatively. Two radiologists interpreted CT and MR images for detecting and staging each patient independently. With the reference of post-operative histopathological findings, T staging accuracy of CT and MR imaging was calculated and compared. Inter-observer agreement was also evaluated.
Overall T staging accuracy in MR including DWI was significantly higher than that in CT imaging(87.8% vs. 65.9%, P=0.004). MR had a better inter-observer agreement than CT(Kappa=0.813, 0.603, respectively).
MR including DWI can improve preoperative T staging accuracy of gastric cancer significantly, which deserves recommendation for clinical application.
比较CT及包括弥散加权成像（DWI）在内的MR在胃癌术前诊断及T分期中的准确性。
前瞻性纳入2011年11月至2012年8月间经胃镜活检证实的41例胃癌患者。术前行增强CT及MR成像（包括DWI、T2加权成像及动态增强成像）检查。两名放射科医生独立解读CT及MR图像，对每位患者进行检测及分期。以术后组织病理学检查结果为参照，计算并比较CT及MR成像的T分期准确性。同时评估观察者间的一致性。
包括DWI在内的MR总体T分期准确性显著高于CT成像（87.8%对65.9%，P = 0.004）。MR的观察者间一致性优于CT（Kappa值分别为0.813、0.603）。
包括DWI在内的MR可显著提高胃癌术前T分期准确性，值得临床推荐应用。
