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超声内镜对胃癌分期的准确性

Accuracy of Endoscopic Ultrasonography for Gastric Cancer Staging.

作者信息

Sacerdotianu Victor Mihai, Ungureanu Bogdan Silviu, Iordache Sevastita, Filip Maria Monalisa, Pirici Daniel, Liliac Ilona Mihaela, Saftoiu Adrian

机构信息

University of Medicine and Pharmacy of Craiova, Research Center of Gastroenterology and Hepatology, Craiova, Romania.

University of Medicine and Pharmacy of Craiova, Department of Histology, Craiova, Romania.

出版信息

Curr Health Sci J. 2022 Jan-Mar;48(1):88-94. doi: 10.12865/CHSJ.48.01.13. Epub 2022 Mar 31.

Abstract

Gastric cancer remains a health problem, with treatment indications varying with the TNM stage. We aimed in this study to highlight the role of EUS in GC patients and also to calculate the accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of EUS for T and N staging in our group of patients with this disease. In this study, we included 41 GC patients, and individual values for every T stage accuracy, sensitivity, specificity, PPV, NPV, correct staging, understaging, and overstaging were calculated. EUS overall accuracy for T staging was 58.53%, with the highest sensitivity reached for the T4 stage, 95.83%. For N+vs. N-staging, EUS accuracy was 68.29%, with a sensitivity of 75% and a specificity of 44.44%. The positive and negative predicted values for the presence or absence of nodal disease were 82.75%, respectively 33.33%. In conclusion, this study confirmed the importance of EUS for the assessment of GC T and N stage and highlighted the role of this tool in the detection of liver micrometastasis unrevealed by other imaging techniques like abdominal ultrasound or MSCT.

摘要

胃癌仍然是一个健康问题,其治疗指征因TNM分期而异。我们开展本研究旨在突出超声内镜(EUS)在胃癌患者中的作用,并计算EUS对我们这组胃癌患者T分期和N分期的准确性、敏感性、特异性、阳性预测值(PPV)和阴性预测值(NPV)。在本研究中,我们纳入了41例胃癌患者,并计算了每个T分期的准确性、敏感性、特异性、PPV、NPV、正确分期、分期不足和分期过度的个体值。EUS对T分期的总体准确率为58.53%,T4期的敏感性最高,为95.83%。对于N+与N-分期,EUS的准确率为68.29%,敏感性为75%,特异性为44.44%。有无淋巴结疾病的阳性和阴性预测值分别为82.75%和33.33%。总之,本研究证实了EUS对评估胃癌T和N分期的重要性,并突出了该工具在检测腹部超声或多层螺旋CT(MSCT)等其他成像技术未发现的肝微转移中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e194/9289590/e032282575b0/CHSJ-48-01-88-fig1.jpg

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