18F-FDG-PET和PET/CT在接受钇-90选择性内照射治疗的结直肠癌肝转移患者中的作用：一项基于证据的首次综述。
The role of 18F-FDG-PET and PET/CT in patients with colorectal liver metastases undergoing selective internal radiation therapy with yttrium-90: a first evidence-based review.
作者信息
Annunziata Salvatore, Treglia Giorgio, Caldarella Carmelo, Galiandro Federica
机构信息
Department of Bioimaging and Radiological Sciences, Institute of Nuclear Medicine, Catholic University of the Sacred Heart, Largo Agostino Gemelli 8, 00168 Rome, Italy.
Department of Nuclear Medicine and PET Center, Oncology Institute of Southern Switzerland, via Ospedale 12, 6500 Bellinzona, Switzerland.
出版信息
ScientificWorldJournal. 2014 Feb 2;2014:879469. doi: 10.1155/2014/879469. eCollection 2014.
PURPOSE
To provide a first evidence-based review of the literature on the role of fluorine-18-fluorodeoxyglucose positron emission tomography and positron emission tomography/computed tomography (FDG-PET and PET/CT) in patients with colorectal liver metastases (CRLM) undergoing selective internal radiation therapy (SIRT) with yttrium-90 ((90)Y) microspheres.
METHODS
A comprehensive computer literature search was conducted to find relevant published articles on whole-body FDG-PET or PET/CT in patients with CRLM undergoing SIRT.
RESULTS
We identified 19 studies including 833 patients with CRLM undergoing SIRT. The role of FDG-PET or PET/CT was analysed in treatment planning, treatment response evaluation, and as prognostic tool.
CONCLUSION
FDG-PET and PET/CT provide additional information in treatment evaluation of CRLM patients treated with SIRT and may have a role in treatment planning and patient selection. FDG-PET/CT is emerging as good prognostic tool in these patients.
目的
对有关氟-18-氟脱氧葡萄糖正电子发射断层扫描和正电子发射断层扫描/计算机断层扫描（FDG-PET和PET/CT）在接受钇-90（90Y）微球选择性内放射治疗（SIRT）的结直肠癌肝转移（CRLM）患者中的作用的文献进行首次循证综述。
方法
进行全面的计算机文献检索，以查找有关接受SIRT的CRLM患者全身FDG-PET或PET/CT的相关已发表文章。
结果
我们确定了19项研究，包括833例接受SIRT的CRLM患者。分析了FDG-PET或PET/CT在治疗计划、治疗反应评估以及作为预后工具方面的作用。
结论
FDG-PET和PET/CT在接受SIRT治疗的CRLM患者的治疗评估中提供了额外信息，可能在治疗计划和患者选择中发挥作用。FDG-PET/CT正在成为这些患者良好的预后工具。
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