哮喘-慢性阻塞性肺疾病重叠综合征（ACOS）：当前文献综述
Asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS): current literature review.
作者信息
Papaiwannou Antonis, Zarogoulidis Paul, Porpodis Konstantinos, Spyratos Dionysios, Kioumis Ioannis, Pitsiou Georgia, Pataka Athanasia, Tsakiridis Kosmas, Arikas Stamatis, Mpakas Andreas, Tsiouda Theodora, Katsikogiannis Nikolaos, Kougioumtzi Ioanna, Machairiotis Nikolaos, Siminelakis Stavros, Kolettas Alexander, Kessis George, Beleveslis Thomas, Zarogoulidis Konstantinos
机构信息
1 Pulmonary Department-Oncology Unit, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 2 Cardiology Department, "Saint Luke" Private Clinic, Thessaloniki, Panorama, Greece ; 3 Surgery Department (NHS), University General Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis, Greece ; 4 Internal Medicine Department, "Theageneio" Cancer Hospital, Thessaloniki, Greece ; 5 Department of Cardiac Surgery, University of Ioannina, School of Medicine, Greece ; 6 Anesthisiology Department, 7 Oncology Department, 8 Cardiology Department, "Saint Luke" Private Clinic, Thessaloniki, Panorama, Greece.
出版信息
J Thorac Dis. 2014 Mar;6 Suppl 1(Suppl 1):S146-51. doi: 10.3978/j.issn.2072-1439.2014.03.04.
Asthma and chronic obstructive pulmonary disease (COPD) are chronic diseases, very common in general population. These obstructive airway illnesses are manifested with chronic inflammation affecting the whole respiratory tract. Obstruction is usually intermittent and reversible in asthma, but is progressive and irreversible in COPD. Asthma and COPD may overlap and converge, especially in older people [overlap syndrome-asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS)]. Although ACOS accounts approximately 15-25% of the obstructive airway diseases, is not well recognised because of the structure of clinical trials. COPD studies exclude asthma patients and asthma studies exclude COPD patients, respectively. It is crucial to define asthma, COPD and overlap syndrome (ACOS), as notable clinical entities, which they share common pathologic and functional features, but they are characterized from differences in lung function, acute exacerbations, quality of life, hospital impact and mortality.
哮喘和慢性阻塞性肺疾病（COPD）是慢性疾病，在普通人群中非常常见。这些阻塞性气道疾病表现为影响整个呼吸道的慢性炎症。在哮喘中，阻塞通常是间歇性且可逆的，但在COPD中是进行性且不可逆的。哮喘和COPD可能重叠并合并，尤其是在老年人中[重叠综合征——哮喘-慢性阻塞性肺疾病重叠综合征（ACOS）]。尽管ACOS约占阻塞性气道疾病的15%-25%，但由于临床试验的结构，它并未得到充分认识。COPD研究分别排除哮喘患者，哮喘研究排除COPD患者。将哮喘、COPD和重叠综合征（ACOS）定义为显著的临床实体至关重要，因为它们具有共同的病理和功能特征，但在肺功能、急性加重、生活质量、医院影响和死亡率方面存在差异。
Zotero 插件