Spyratos Dionysios, Zarogoulidis Paul, Porpodis Konstantinos, Angelis Nikolaos, Papaiwannou Antonios, Kioumis Ioannis, Pitsiou Georgia, Pataka Athanasia, Tsakiridis Kosmas, Mpakas Andreas, Arikas Stamatis, Katsikogiannis Nikolaos, Kougioumtzi Ioanna, Tsiouda Theodora, Machairiotis Nikolaos, Siminelakis Stavros, Argyriou Michael, Kotsakou Maria, Kessis George, Kolettas Alexander, Beleveslis Thomas, Zarogoulidis Konstantinos
1 Pulmonary Department-Oncology Unit, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 2 Cardiology Department, "Saint Luke" Private Clinic, Thessaloniki, Panorama, Greece ; 3 Surgery Department (NHS), University General Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis, Greece ; 4 Internal Medicine Department, "Theageneio" Cancer Hospital, Thessaloniki, Greece ; 5 Department of Cardiac Surgery, University of Ioannina, School of Medicine, Greece ; 6 2nd Cardiac Surgery Department, "Evangelismos" General Hospital, Athens, Greece ; 7 Electrophysiology Department, "Saint Luke" Private Clinic, Thessaloniki, Panorama, Greece ; 8 Oncology Department, "Saint Luke" Private Clinic, Thessaloniki, Panorama, Greece ; 9 Anesthisiology Department, "Saint Luke" Private Clinic, Thessaloniki, Panorama, Greece ; 10 Cardiology Department, "Saint Luke" Private Clinic, Thessaloniki, Panorama, Greece.
J Thorac Dis. 2014 Mar;6 Suppl 1(Suppl 1):S162-6. doi: 10.3978/j.issn.2072-1439.2014.03.06.
During the last decades lung cancer is the leading cause of death worldwide for both sexes. Even though cigarette smoking has been proved to be the main causative factor, many other agents (e.g., occupational exposure to asbestos or heavy metals, indoor exposure to radon gas radiation, particulate air pollution) have been associated with its development. Recently screening programs proved to reduce mortality among heavy-smokers although establishment of such strategies in everyday clinical practice is much more difficult and unknown if it is cost effective compared to other neoplasms (e.g., breast or prostate cancer). Adding severe comorbidities (coronary heart disease, COPD) to the above reasons as cigarette smoking is a common causative factor, we could explain the low surgical resection rates (approximately 20-30%) for lung cancer patients. Three clinical guidelines reports of different associations have been published (American College of Chest Physisians, British Thoracic Society and European Respiratory Society/European Society of Thoracic Surgery) providing detailed algorithms for preoperative assessment. In the current mini review, we will comment on the preoperative evaluation of lung cancer patients.
在过去几十年中,肺癌是全球男女死亡的主要原因。尽管吸烟已被证明是主要致病因素,但许多其他因素(如职业接触石棉或重金属、室内接触氡气辐射、颗粒物空气污染)也与其发病有关。最近的筛查项目证明可降低重度吸烟者的死亡率,不过在日常临床实践中制定此类策略要困难得多,而且与其他肿瘤(如乳腺癌或前列腺癌)相比,其成本效益如何尚不清楚。由于吸烟是常见致病因素,再加上严重的合并症(冠心病、慢性阻塞性肺疾病),我们可以解释肺癌患者手术切除率较低(约20%-30%)的原因。不同协会已发表了三份临床指南报告(美国胸科医师学会、英国胸科学会以及欧洲呼吸学会/欧洲胸外科协会),提供了详细的术前评估算法。在本次小型综述中,我们将对肺癌患者的术前评估进行评论。