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健康阿萨姆人群血清尿酸的参考范围。

Reference Ranges for Serum Uric Acid among Healthy Assamese People.

作者信息

Das Madhumita, Borah N C, Ghose M, Choudhury N

机构信息

Biochemistry Lab, GNRC Hospitals, Dispur, Guwahati 6, 781006, India ; GNRC Lab Services, GNRC Hospitals, Dispur, Guwahati 781006, India.

Biochemistry Lab, GNRC Hospitals, Dispur, Guwahati 6, 781006, India.

出版信息

Biochem Res Int. 2014;2014:171053. doi: 10.1155/2014/171053. Epub 2014 Jan 9.

Abstract

This study was designed to establish reference ranges for serum uric acid among healthy adult Assamese population. Samples from 1470 aged 35-86 years were used to establish age and sex related reference range by the centile method (central 95 percentile) for serum uric acid level. There were 51% (n = 754) males and 49% (n = 716) females; 75.9% (n = 1115) of them were from urban area and the rest 24.1% (n = 355) were from the rural area. Majority of the population were nonvegetarian (98.6%, n = 1450) and only 1.4% (n = 20) were vegetarian. The mean age, weight, height, and uric acid of the studied group were 53.6 ± 11.3 years, 62.6 ± 10.5 kg, 160 ± 9.4 cm, and 5.5 ± 1.4 mg/dL, respectively. There is a statistically significant difference in the mean value of the abovementioned parameters between male and female. The observed reference range of uric acid in the population is 2.6-8.2 mg/dL which is wider than the current reference range used in the laboratory. Except gender (P < 0.0001), we did not find any significant relation of uric acid with other selected factors.

摘要

本研究旨在确定健康成年阿萨姆人群血清尿酸的参考范围。采用百分位数法(中心95%位数),对1470名年龄在35 - 86岁的样本进行分析,以建立血清尿酸水平与年龄和性别的相关参考范围。其中男性占51%(n = 754),女性占49%(n = 716);75.9%(n = 1115)来自城市地区,其余24.1%(n = 355)来自农村地区。大多数人(98.6%,n = 1450)非素食,只有1.4%(n = 20)为素食者。研究组的平均年龄、体重、身高和尿酸分别为53.6 ± 11.3岁、62.6 ± 10.5 kg、160 ± 9.4 cm和5.5 ± 1.4 mg/dL。上述参数的平均值在男性和女性之间存在统计学显著差异。该人群中观察到的尿酸参考范围为2.6 - 8.2 mg/dL,比实验室目前使用的参考范围更宽。除性别外(P < 0.0001),我们未发现尿酸与其他所选因素之间存在任何显著关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21e6/3942193/d96f783dee89/BRI2014-171053.001.jpg

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