螯合辅助烯烃水酯交换反应：新型钌催化剂体系和配体效应。

Chelation-assisted hydroesterification of alkenes: new ruthenium catalyst systems and ligand effects.

机构信息

Center for Catalytic Hydrocarbon Functionalizations, Institute of Basic Science (IBS) , Daejeon 305-701, Korea.

出版信息

Org Lett. 2014 Apr 4;16(7):2010-3. doi: 10.1021/ol500579n. Epub 2014 Mar 27.

Abstract

New types of ruthenium catalysts were developed for the chelation-assisted intermolecular olefin hydroesterification that employs 2-pyridylmethyl formate as an ester source. Two classes of ligands, NHCs and phosphines, were found to facilitate the reaction delivering isomeric ester products (linear versus branched) with different ratios, thus allowing access to ligand-guided selective hydroesterification.

摘要

开发了新型钌催化剂用于螯合辅助的烯烃间酯氢酯化反应，使用 2-吡啶基甲酯作为酯源。发现两类配体，NHCs 和膦配体，可促进反应，得到不同比例的异构体酯产物（直链与支链），从而实现配体导向的选择性酯氢酯化。