当前腹部脓毒症概念：WSES 立场文件。
Current concept of abdominal sepsis: WSES position paper.
机构信息
Department of Surgery, Macerata Hospital, Macerata, Italy.
出版信息
World J Emerg Surg. 2014 Mar 27;9(1):22. doi: 10.1186/1749-7922-9-22.
Abstract
Although sepsis is a systemic process, the pathophysiological cascade of events may vary from region to region.Abdominal sepsis represents the host's systemic inflammatory response to bacterial peritonitis.It is associated with significant morbidity and mortality rates, and is the second most common cause of sepsis-related mortality in the intensive care unit.The review focuses on sepsis in the specific setting of severe peritonitis.
摘要
尽管败血症是一种全身性疾病，但病理生理级联反应可能因地域不同而有所差异。腹腔感染代表了机体对细菌性腹膜炎的全身性炎症反应，它与高发病率和高死亡率相关，是重症监护病房中导致与败血症相关死亡的第二大常见原因。本文重点关注严重腹膜炎这一特定环境下的败血症。
相似文献
1
Current concept of abdominal sepsis: WSES position paper.当前腹部脓毒症概念：WSES 立场文件。
World J Emerg Surg. 2014 Mar 27;9(1):22. doi: 10.1186/1749-7922-9-22.
2
Management of abdominal sepsis--a paradigm shift?腹部脓毒症的管理——是一种范式转变吗？
Anaesthesiol Intensive Ther. 2015;47(4):400-8. doi: 10.5603/AIT.a2015.0026. Epub 2015 May 14.
3
Management of secondary peritonitis.继发性腹膜炎的管理
Ann Surg. 1996 Jul;224(1):10-8. doi: 10.1097/00000658-199607000-00003.
4
[Peritonitis: main reason of severe sepsis in surgical intensive care].[腹膜炎：外科重症监护中严重脓毒症的主要原因]
Zentralbl Chir. 2007 Apr;132(2):130-7. doi: 10.1055/s-2006-960478.
5
Intra-abdominal sepsis: newer interventional and antimicrobial therapies.腹腔内脓毒症：新型介入治疗与抗菌治疗
Infect Dis Clin North Am. 2009 Sep;23(3):593-608. doi: 10.1016/j.idc.2009.04.007.
6
[Prospective multicenter comparative study of the management of peritonitis. Quality assurance in severe intra-abdominal infection].[腹膜炎治疗的前瞻性多中心比较研究。严重腹腔内感染的质量保证]
Zentralbl Chir. 2000;125 Suppl 2:199-204.
7
Global validation of the WSES Sepsis Severity Score for patients with complicated intra-abdominal infections: a prospective multicentre study (WISS Study).WSES腹腔内复杂感染患者脓毒症严重程度评分的全球验证：一项前瞻性多中心研究（WISS研究）
World J Emerg Surg. 2015 Dec 16;10:61. doi: 10.1186/s13017-015-0055-0. eCollection 2015.
8
Wound healing in sepsis and trauma.脓毒症和创伤中的伤口愈合
Shock. 1997 Dec;8(6):391-401.
9
[Analysis of organ failure and mortality in sepsis due to secondary peritonitis].[继发性腹膜炎所致脓毒症的器官衰竭与死亡率分析]
Med Intensiva. 2013 Oct;37(7):461-7. doi: 10.1016/j.medin.2012.07.010. Epub 2012 Oct 6.
10
The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections.从全球视角看腹腔内感染的管理：2017 年 WSES 腹腔内感染管理指南。
World J Emerg Surg. 2017 Jul 10;12:29. doi: 10.1186/s13017-017-0141-6. eCollection 2017.
引用本文的文献
1
Intra-abdominal sepsis in critically ill surgical patients: the relationship between cumulative fluid balance and serum sodium and chloride levels and in-hospital mortality.重症外科患者的腹腔内脓毒症：累积液体平衡与血清钠、氯水平及住院死亡率之间的关系
Front Med (Lausanne). 2025 Jul 16;12:1608388. doi: 10.3389/fmed.2025.1608388. eCollection 2025.
2
Factors Associated with Short-Term Surgical Outcomes Among Women Presenting with Pelvic Peritonitis at Bugando Medical Centre Mwanza, Tanzania.坦桑尼亚姆万扎布甘多医疗中心盆腔腹膜炎女性患者短期手术结局的相关因素
East Afr Health Res J. 2023;7(2):147-157. doi: 10.24248/eahrj.v7i2.726. Epub 2023 Nov 30.
3
Monitoring Circulating Myeloid Cells in Peritonitis with an In Vivo Imaging Flow Cytometer.利用体内成像流式细胞仪监测腹膜炎中的循环髓系细胞。
Biomolecules. 2024 Jul 23;14(8):886. doi: 10.3390/biom14080886.
4
Intra-abdominal infections survival guide: a position statement by the Global Alliance For Infections In Surgery.腹腔内感染生存指南：全球外科感染联盟的立场声明。
World J Emerg Surg. 2024 Jun 8;19(1):22. doi: 10.1186/s13017-024-00552-9.
5
Sepsis-Related Lung Injury and the Complication of Extrapulmonary Pneumococcal Pneumonia.脓毒症相关肺损伤及肺外肺炎链球菌肺炎并发症
Diseases. 2024 Apr 3;12(4):72. doi: 10.3390/diseases12040072.
6
Greater Omentum: Multifaceted Interactions in Neurological Recovery and Disease Progression.大网膜：在神经恢复和疾病进展中的多方面相互作用。
Aging Dis. 2024 Feb 19;15(6):2381-2394. doi: 10.14336/AD.2024.0213.
7
The Association of Polish Surgeons (APS) clinical guidelines for the use of laparoscopy in the management of abdominal emergencies. Part I.波兰外科医生协会（APS）关于腹腔镜检查在腹部急症处理中应用的临床指南。第一部分。
Wideochir Inne Tech Maloinwazyjne. 2023 Jun;18(2):187-212. doi: 10.5114/wiitm.2023.127877. Epub 2023 Jun 2.
8
Source control in emergency general surgery: WSES, GAIS, SIS-E, SIS-A guidelines.急诊普通外科中的源头控制：WSES、GAIS、SIS-E、SIS-A 指南。
World J Emerg Surg. 2023 Jul 21;18(1):41. doi: 10.1186/s13017-023-00509-4.
9
Gut microbiome diversity of porcine peritonitis model of sepsis.猪脓毒症腹膜炎模型的肠道微生物多样性。
Sci Rep. 2022 Oct 19;12(1):17430. doi: 10.1038/s41598-022-21079-6.
10
Vacuum-assisted closure versus on-demand relaparotomy in patients with secondary peritonitis-the VACOR trial: protocol for a randomised controlled trial.负压封闭引流与按需再次剖腹术治疗继发性腹膜炎的比较(VACOR 试验)：一项随机对照试验的方案。
World J Emerg Surg. 2022 May 26;17(1):25. doi: 10.1186/s13017-022-00427-x.
本文引用的文献
1
Abdominal damage control surgery and reconstruction: world society of emergency surgery position paper.腹部损伤控制性手术与重建：世界急诊外科学会立场文件。
World J Emerg Surg. 2013 Dec 17;8(1):53. doi: 10.1186/1749-7922-8-53.
2
Current status of the open abdomen treatment for intra-abdominal infection.腹腔内感染开放腹腔治疗的现状
Gastroenterol Res Pract. 2013;2013:532013. doi: 10.1155/2013/532013. Epub 2013 Oct 2.
3
Acute kidney injury is surprisingly common and a powerful predictor of mortality in surgical sepsis.急性肾损伤在外科脓毒症中非常常见，也是死亡率的有力预测指标。
J Trauma Acute Care Surg. 2013 Sep;75(3):432-8. doi: 10.1097/TA.0b013e31829de6cd.
4
Local and systemic innate immune response to secondary human peritonitis.对继发性人类腹膜炎的局部和全身先天性免疫反应。
Crit Care. 2013 Sep 12;17(5):R201. doi: 10.1186/cc12895.
5
Severe sepsis and septic shock.严重脓毒症和脓毒性休克。
N Engl J Med. 2013 Aug 29;369(9):840-51. doi: 10.1056/NEJMra1208623.
6
Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome.腹腔内高压和腹腔间隔室综合征：世界腹主动脉瘤学会更新的共识定义和临床实践指南。
Intensive Care Med. 2013 Jul;39(7):1190-206. doi: 10.1007/s00134-013-2906-z. Epub 2013 May 15.
7
Use of the PiCCO system in critically ill patients with septic shock and acute respiratory distress syndrome: a study protocol for a randomized controlled trial.应用脉搏指示剂连续心排血量监测技术（PiCCO）治疗感染性休克合并急性呼吸窘迫综合征患者的随机对照研究方案
Trials. 2013 Feb 1;14:32. doi: 10.1186/1745-6215-14-32.
8
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012.拯救脓毒症运动：严重脓毒症和脓毒性休克管理国际指南，2012 年。
Intensive Care Med. 2013 Feb;39(2):165-228. doi: 10.1007/s00134-012-2769-8. Epub 2013 Jan 30.
9
Tigecycline: an update.替加环素：更新。
Diagn Microbiol Infect Dis. 2013 Apr;75(4):331-6. doi: 10.1016/j.diagmicrobio.2012.12.004. Epub 2013 Jan 26.
10
2013 WSES guidelines for management of intra-abdominal infections.2013 WSES 腹腔内感染管理指南。
World J Emerg Surg. 2013 Jan 8;8(1):3. doi: 10.1186/1749-7922-8-3.
Zotero 插件