Ndoye M, Niang L, Gandaho K I, Jalloh M, Labou I, Gueye S
Hôpital général de Grand Yoff, Dakar, Sénégal.
Hôpital général de Grand Yoff, Dakar, Sénégal.
Prog Urol. 2014 Apr;24(5):271-5. doi: 10.1016/j.purol.2013.08.317. Epub 2013 Sep 25.
Prostate cancer is a common disease, which continues to be discovered at advanced stages in Africa, despite improved diagnostic tools.
The authors report the experience of the Department of Urology, General Hospital of Grand Yoff Dakar in the diagnostic of advanced prostate cancer.
This was a retrospective descriptive study on patients followed for advanced prostate cancer during the period from January 1st, 2004 to May 31st, 2010.
There were 102 people aged from 51 to 96 years with an average of 71 ± 9 years. A comorbid condition was associated in 24.5 % of cases. The circumstances of discovery were pain (32 cases), neurological signs (17 cases), and urinary disorders. DRE had objectified an abnormality in all patients. The serum levels of prostate specific antigen ranged from 5.88 ng/mL to 21,660 ng/mL, with an average of 1447.57 ± 812 ng/mL. A prostate biopsy was performed in 44 patients and prostatic adenocarcinoma was found in 97.7 % of cases with Gleason scores greater than 7 (33 cases). We found different metastatic sites at vertebral column (23 cases), at lung (14 cases), and on pelvic bones (11 cases).
The prostate cancer is a serious condition with high morbidity and mortality. The diagnosis is not made early in developing countries. We need a strategic plan to improve the early screening and we should develop supportive care too because of the high number of advanced cases diagnosed in our context.
前列腺癌是一种常见疾病，尽管诊断工具有所改进，但在非洲仍不断有晚期病例被发现。
作者报告达喀尔大尤夫综合医院泌尿外科在晚期前列腺癌诊断方面的经验。
这是一项对2004年1月1日至2010年5月31日期间接受晚期前列腺癌治疗的患者进行的回顾性描述性研究。
共有102人，年龄在51岁至96岁之间，平均年龄为71±9岁。24.5%的病例伴有合并症。发现的情况包括疼痛（32例）、神经症状（17例）和泌尿系统疾病。所有患者的直肠指检均发现异常。前列腺特异性抗原血清水平在5.88 ng/mL至21,660 ng/mL之间，平均为1447.57±812 ng/mL。44例患者进行了前列腺活检，97.7%（33例）的病例发现前列腺腺癌，Gleason评分大于7。我们发现不同的转移部位，脊柱（23例）、肺部（14例）和骨盆骨（11例）。
前列腺癌是一种严重疾病，发病率和死亡率都很高。在发展中国家，诊断不能早期进行。我们需要一个战略计划来改善早期筛查，并且由于我们这里诊断出的晚期病例数量众多，我们也应该发展支持性护理。
