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[实验性病毒感染中的脂质过氧化作用以及干扰素和α-生育酚对其的影响]

[Lipid peroxidation in experimental viral infection and the effect on it of interferons and alpha-tocopherol].

作者信息

Ananenko A A, Malinovskaia V V, Klembovskiĭ A I, Politova L N, Pertseva N G

出版信息

Vopr Med Khim. 1988 Nov-Dec;34(6):86-9.

PMID:2467439
Abstract

Lipid peroxidation as well as effects of various interferons (native, from fibroblasts of new born and adult animals) on the peroxidation were studied in blood plasma, erythrocytes, liver and kidney tissues of mice with viral infection. These interferons, simultaneously with antiviral action, exhibited the positive effect on lipid peroxidation, while the interferon from fibroblasts of newborns produced the side reactions. Simultaneous use of the interferon and alpha-tocopherol removed these side reactions.

摘要

在病毒感染小鼠的血浆、红细胞、肝脏和肾脏组织中,研究了脂质过氧化以及各种干扰素(天然的、来自新生动物和成体动物成纤维细胞的)对过氧化的影响。这些干扰素在发挥抗病毒作用的同时,对脂质过氧化呈现出积极影响,而来自新生动物成纤维细胞的干扰素产生了副作用。同时使用干扰素和α-生育酚消除了这些副作用。

相似文献

1
[Lipid peroxidation in experimental viral infection and the effect on it of interferons and alpha-tocopherol].[实验性病毒感染中的脂质过氧化作用以及干扰素和α-生育酚对其的影响]
Vopr Med Khim. 1988 Nov-Dec;34(6):86-9.
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[The effect of reaferon and alpha-tocopherol on lipid peroxidation in experimental influenza].[干扰素和α-生育酚对实验性流感中脂质过氧化的影响]
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Effect of immobilization, cold and cold-restraint stress on liver monooxygenase activity and lipid peroxidation of influenza virus-infected mice.固定、寒冷及冷束缚应激对流感病毒感染小鼠肝脏单加氧酶活性和脂质过氧化的影响。
Arch Toxicol. 2002 Mar;76(2):96-103. doi: 10.1007/s00204-001-0306-6. Epub 2002 Feb 6.
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[The effect of alpha-tocopherol in water-soluble form on human erythrocyte membranes while in contact with oxygen].[水溶性α-生育酚在与氧气接触时对人红细胞膜的影响]
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[Age-related characteristics of triglyceride, secondary lipid peroxidation products and alpha-tocopherol levels in the tissues of female rats].[雌性大鼠组织中甘油三酯、继发性脂质过氧化产物及α-生育酚水平的年龄相关特征]
Fiziol Zh (1978). 1992 May-Jun;38(3):85-9.
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[The role of lipid peroxidation in post-stress aggravation of influenza and the corrective effect od ionol].[脂质过氧化在应激后流感病情加重中的作用及维生素E的纠正作用]
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Pharmacodynamic of the antioxidant action of alpha-tocopherol and its derivatives in liver, brain, heart and skeletal muscles.α-生育酚及其衍生物在肝脏、大脑、心脏和骨骼肌中的抗氧化作用的药效学。
Acta Physiol Pharmacol Bulg. 2000;25(1):19-26.

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