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单侧多节段经椎板间开窗术:一种治疗颈髓内病变的微创入路。

Unilateral multilevel interlaminar fenestration: a minimally invasive approach for cervical intramedullary lesions.

机构信息

Department of Neurosurgery, Changzheng Hospital, Second Military Medical University, No. 415 FengYang Road, Shanghai 200003, China.

Department of Neurosurgery, Changzheng Hospital, Second Military Medical University, No. 415 FengYang Road, Shanghai 200003, China.

出版信息

J Clin Neurosci. 2014 Jul;21(7):1196-204. doi: 10.1016/j.jocn.2013.10.025. Epub 2014 Jan 2.

Abstract

The traditional approach for cervical intramedullary lesions is laminectomy, but the procedure may result in spinal instability and spinal deformity. Unilateral multilevel interlaminar fenestration (UMIF) is an alternative minimally invasive approach that may have great advantages in preserving spinal stability. However its use in cervical intramedullary lesions is rare, and the indications, safety and limitations of this approach for cervical intramedullary lesions are still under investigation. We report five patients (three males, two females, age range 12-46 years) who were treated between 2010 and 2011 for cervical intramedullary lesions. The lesions included three ependymomas, one astrocytoma and one ependymal cyst, and the locations of the lesions were at the medulla-T2, C4-T1, C5-C7, C4-C7 and C6-C7. All of these lesions were completely removed through UMIF, and all patients had stable or improved neurological status after surgery. No recurrences or spinal deformities were detected during the follow-up period which ranged from 24 to 35 months (mean=27.4 months). UMIF is a feasible approach for selected cervical intramedullary lesions. This approach allows complete resection of multilevel lesions without increasing the risk of injury to the spinal cord, and minimizing the risk of postoperative spinal instability. The indications for and limitations of UMIF are discussed.

摘要

传统的颈椎髓内病变的治疗方法是椎板切除术,但该手术可能导致脊柱不稳定和脊柱畸形。单侧多节段板间开窗术(UMIF)是一种替代的微创方法,在保持脊柱稳定性方面可能具有很大的优势。然而,其在颈椎髓内病变中的应用很少,该方法治疗颈椎髓内病变的适应证、安全性和局限性仍在研究中。我们报告了 5 例(男 3 例,女 2 例,年龄 12-46 岁)于 2010 年至 2011 年间接受治疗的颈椎髓内病变患者。病变包括 3 例室管膜瘤、1 例星形细胞瘤和 1 例室管膜囊肿,病变部位分别位于颈髓-T2、C4-T1、C5-C7、C4-C7 和 C6-C7。所有这些病变均通过 UMIF 完全切除,所有患者术后神经功能均稳定或改善。在 24 至 35 个月(平均 27.4 个月)的随访期间,未发现复发或脊柱畸形。UMIF 是一种治疗选择的颈椎髓内病变的可行方法。该方法可实现多节段病变的完全切除,而不会增加脊髓损伤的风险,并且最小化术后脊柱不稳定的风险。讨论了 UMIF 的适应证和局限性。

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